1354376-72-9

Basic information

• Product Name: C₁₄H₁₆N₂O₄
• Synonyms: C₁₄H₁₆N₂O₄
• CAS NO: 1354376-72-9
• Molecular Weight: 276.292
• Mol File: 1354376-72-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₆N₂O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₆N₂O₄(1354376-72-9)
• EPA Substance Registry System: C₁₄H₁₆N₂O₄(1354376-72-9)

Safety Data

• Hazardous Substances Data: 1354376-72-9(Hazardous Substances Data)

Upstream product

• 13331-23-2 fur-2-ylboronic acid 
• 3290-99-1 4-methoxybenzoic acid hydrazide 
• 141-46-8 Glycolaldehyde 
• 23147-58-2 glycolaldehyde dimer 

Relevant articles and documents

Combining the petasis 3-component reaction with multiple modes of cyclization: A build/couple/pair strategy for the synthesis of densely functionalized small molecules

A build/couple/pair strategy for the synthesis of complex and densely functionalized small molecules is presented. The strategy relies on synthetically tractable building blocks (build), that is, diversely substituted hydrazides, α-hydroxy aldehydes, and boronic acids, which undergo Petasis 3-component reactions (couple) to afford densely functionalized anti-hydrazido alcohols. The resulting scaffolds can subsequently be converted via chemoselective cyclization reactions (pair), including intramolecular Diels-Alder or Ru-alkylidene catalyzed ring-closing metathesis, into sets of structurally diverse heterocycles in good yields in only 3-4 steps.