1354495-16-1

Basic information

• Product Name: (-)-(5S)-4-(4,4-difluorocyclohexyl)-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-7,7-dimethyl-2-{1-[5-(2-methylpropoxy)pyrimidine-2-yl]piperidin-4-yl}-5,6,7,8-tetrahydroquinoline-5-ol
• Synonyms: (-)-(5S)-4-(4,4-difluorocyclohexyl)-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-7,7-dimethyl-2-{1-[5-(2-methylpropoxy)pyrimidine-2-yl]piperidin-4-yl}-5,6,7,8-tetrahydroquinoline-5-ol
• CAS NO: 1354495-16-1
• Molecular Weight: 704.799
• Mol File: 1354495-16-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (-)-(5S)-4-(4,4-difluorocyclohexyl)-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-7,7-dimethyl-2-{1-[5-(2-methylpropoxy)pyrimidine-2-yl]piperidin-4-yl}-5,6,7,8-tetrahydroquinoline-5-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(5S)-4-(4,4-difluorocyclohexyl)-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-7,7-dimethyl-2-{1-[5-(2-methylpropoxy)pyrimidine-2-yl]piperidin-4-yl}-5,6,7,8-tetrahydroquinoline-5-ol(1354495-16-1)
• EPA Substance Registry System: (-)-(5S)-4-(4,4-difluorocyclohexyl)-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-7,7-dimethyl-2-{1-[5-(2-methylpropoxy)pyrimidine-2-yl]piperidin-4-yl}-5,6,7,8-tetrahydroquinoline-5-ol(1354495-16-1)

Safety Data

• Hazardous Substances Data: 1354495-16-1(Hazardous Substances Data)

Upstream product

• 1354495-70-7 (-)-(5S)-4-(4,4-difluorocyclohexyl)-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-5-[(4-methoxybenzyl)oxy]-7,7-dimethyl-2-(piperidin-4-yl)-5,6,7,8-tetrahydroquinoline 
• 1354495-94-5 2-[(1-tert-butyloxycarbonyl)piperidin-4-yl]-4-(4,4-difluorocyclohexyl)-3-formyl-5-[(4-methoxybenzyl)oxy]-7,7-dimethyl-5,6,7,8-tetrahydroquinoline 
• 1354495-93-4 2-[(1-tert-butyloxycarbonyl)piperidin-4-yl]-4-(4,4-difluorocyclohexyl)-3-formyl-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-ol 
• 1354495-92-3 2-[(1-tert-butyloxycarbonyl)piperidin-4-yl]-3-cyano-4-(4,4-difluorocyclohexyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline 
• 1354495-91-2 2-[(1-tert-butyloxycarbonyl)piperidin-4-yl]-3-cyano-4-(4,4-difluorocyclohexyl)-7,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline 
• 1354495-90-1 4-(1-amino-2-cyanoethenyl)piperidin-1-carboxylic acid tert-butyl ester 
• 91419-52-2 1-tert-butoxycarbonyl-4-cyanopiperidine 
• 265108-36-9 4,4-difluorocyclohexane carboxyaldehyde 
• 178312-47-5 ethyl 4,4-difluorocyclohexane-1-carboxylate 
• 1354495-72-9 (-)-(5S)-4-(4,4-difluorocyclohexyl)-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-5-[(4-methoxybenzyl)oxy]-7,7-dimethyl-2-{1-[5-(morpholin-4-yl)pyrimidin-2-yl]piperidin-4-yl}-5,6,7,8-tetrahydroquinoline 
• 1354495-71-8 (5S)-2-[1-(5-bromopyrimidin-2-yl)piperidin-4-yl]-4-(4,4-difluorocyclohexyl)-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-5-[(4-methoxybenzyl)oxy]-7,7-dimethyl-5,6,7,8-tetrahydroquinoline 
• 513-38-2 Isobutyl iodide 
• 1354494-81-7 (-)-(5S)-4-(4,4-difluorocyclohexyl)-3-{(S)-fluoro[4-(trifluoromethyl)phenyl]methyl}-2-[1-(5-hydroxypyrimidin-2-yl)piperidin-4-yl]-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-ol 

Relevant articles and documents

Substituted Pyridine Compound

The present invention provides a substituted pyridine compound or a pharmacologically acceptable salt thereof which has excellent CETP inhibition activity and is useful as a medicament. The present invention provides a compound represented by a general formula (I), wherein R1 is H, optionally substituted alkyl, OH, optionally substituted alkoxy, alkylsulfonyl, optionally substituted amino, carboxy, optionally substituted carbonyl, CN, halogeno, optionally substituted phenyl, optionally substituted aromatic heterocyclyl, optionally substituted saturated heterocyclyl, optionally substituted saturated heterocyclyloxy or optionally substituted saturated heterocyclylcarbonyl, etc., and the like.