13545-14-7

Basic information

• Product Name: 2(1H)-Pyrimidinone, 4,6-dimethyl-1-(phenylmethoxy)-
• CAS NO: 13545-14-7
• Molecular Formula: C13H14N2O2
• Molecular Weight: 230.266
• Mol File: 13545-14-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2(1H)-Pyrimidinone, 4,6-dimethyl-1-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Pyrimidinone, 4,6-dimethyl-1-(phenylmethoxy)-(13545-14-7)
• EPA Substance Registry System: 2(1H)-Pyrimidinone, 4,6-dimethyl-1-(phenylmethoxy)-(13545-14-7)

Safety Data

• Hazardous Substances Data: 13545-14-7(Hazardous Substances Data)

Usage

Chemical structure

pyrimidinone with two methyl groups at positions 4 and 6, and a phenylmethoxy group at position 1

Uses

commonly used as a building block in the synthesis of pharmaceuticals and other organic compounds

Upstream product

• 622-33-3 N-benzyloxyamine 
• 7664-93-9 sulfuric acid 
• 2048-50-2 benzyloxyurea 
• 123-54-6 acetylacetone 

Downstream Products

• 300-87-8 3,5-dimethyl-1,2-oxazole 

Relevant articles and documents

N-HYDROXYAMIDE-CONTAINING HETEROCYCLES. PART 3. THE RING TRANSFORMATION OF 1-BENZYLOXY-2(1H)-PYRIMIDINONES INTO 2-ISOXAZOLINES WITH HYDROXYLAMINE

N-Benzyloxyurea was treated various β-diketones on the presence of sulfuric acid in EtOH to give the corresponding 1-benzyloxy-2(1H)-pyrimidinones. 1-Benzyloxy-2(1H)-pyrimidinonesunderwent the ring transformation with hydroxylamine to afford new 5-N-(benzyloxy)urea-attached 2-isoxazolines in addition to known isoxazoles.The MNDO molecular orbital calculation of 1-benzyloxy-4,6-dimethyl-2(1H)-pyrimidinone and the reaction mechanism are also discussed.

N-Hydroxyamide-containing Heterocycles. New Effective Additives for Peptide Synthesis by the Dicyclohexylcarbodiimide Method

N-Hydroxyamide-containing heterocycles, 1-hydroxy-4,6-dimethyl-2(1H)-pyrimidinone and -5,6-dimethyl-2(1H)-pyrazinone, are prepared.Judging from the result of model dipeptide (Z-Ala-Phe-OMe) formation, these compounds are found to be new effective additive