135457-26-0

Basic information

• Product Name: (2S,4R)-2-amino-4-hydroxy-4-phenylbutanoic acid
• Synonyms: (2S,4R)-2-amino-4-hydroxy-4-phenylbutanoic acid
• CAS NO: 135457-26-0
• Molecular Weight: 195.218
• Mol File: 135457-26-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,4R)-2-amino-4-hydroxy-4-phenylbutanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4R)-2-amino-4-hydroxy-4-phenylbutanoic acid(135457-26-0)
• EPA Substance Registry System: (2S,4R)-2-amino-4-hydroxy-4-phenylbutanoic acid(135457-26-0)

Safety Data

• Hazardous Substances Data: 135457-26-0(Hazardous Substances Data)

Upstream product

• 2922-83-0 L-kynurenine 
• 100-52-7 benzaldehyde 

Relevant articles and documents

Kynureninase in organic synthesis : Preparation of γ-hydroxy-α-L-amino acids

Kynureninase, which is known to catalyze the transaldol reaction between benzaldehyde and kynurenine, accepted many kinds of other aromatic aldehydes and propargyl aldehydes as the substrates to afford novel γ-hydroxy-α-L-amino acids. The L-configuration of the α-carbons was confirmed by an enzymatic method using both D- and L-amino acid oxidases. The stereochemistry of the newly formed chiral center (γ-position) in major isomers was determined to be R-configuration by the observed NOEs in the NMR spectroscopy of lactones derived from the γ-hydroxy-α-L-amino acids.