1354787-75-9Relevant articles and documents
Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer
Zhao, Robert Yongxin,Erickson, Hans K.,Leece, Barbara A.,Reid, Emily E.,Goldmacher, Victor S.,Lambert, John M.,Chari, Ravi V. J.
, p. 766 - 782 (2012/03/11)
The synthesis and biological evaluation of phosphate prodrugs of analogues of 1 (CC-1065) and their conjugates with antibodies are described. The phosphate group on the 1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) portion of the compounds conf