135482-70-1 Usage
Description
4-(2-Aminoethyl)benzoic acid tert-butyl ester, also known as Tert-Butyl 4-(2-Aminoethyl)Benzoate, is a chemical compound derived from benzoic acid with an aminoethyl group and a tert-butyl ester functional group. It possesses unique chemical properties due to its structure, making it a versatile molecule for various applications in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
4-(2-Aminoethyl)benzoic acid tert-butyl ester is used as a building block for the synthesis of biologically active small molecules. Its unique structure allows for the development of new drugs with potential therapeutic applications, such as targeting specific receptors or enzymes in the body.
Used in Chemical Industry:
In the chemical industry, 4-(2-Aminoethyl)benzoic acid tert-butyl ester can be utilized as an intermediate in the synthesis of various chemical products. Its functional groups enable further chemical modifications, making it a valuable compound for creating a wide range of specialty chemicals and materials.
Used in Drug Development:
4-(2-Aminoethyl)benzoic acid tert-butyl ester is used as a key component in the development of new drugs for various medical conditions. Its chemical properties allow for the design of molecules with specific biological activities, potentially leading to the discovery of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 135482-70-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,4,8 and 2 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 135482-70:
(8*1)+(7*3)+(6*5)+(5*4)+(4*8)+(3*2)+(2*7)+(1*0)=131
131 % 10 = 1
So 135482-70-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H19NO2/c1-13(2,3)16-12(15)11-6-4-10(5-7-11)8-9-14/h4-7H,8-9,14H2,1-3H3
135482-70-1Relevant articles and documents
Highly Selective Adenosine A2 Receptor Agonists in a Series of N-Alkylated 2-Aminoadenosines
Francis, John E.,Webb, Randy L.,Ghai, Geetha R.,Hutchison, Alan J.,Moskal, Michael A.,et al.
, p. 2570 - 2579 (2007/10/02)
A wide variety of 2-substituted aminoadenosines were prepared for comparison with the moderately A2 receptor selective adenosine agonist 2-anilinoadenosine (CV-1808).High selectivity combined with significant affinity at the A2 receptor in rat membranes was observed for those amines bearing a two-carbon chain to which was attached an aryl, heteroaryl, or alicyclic moiety. 2-(2-Phenethylamino)adenosine (3d), a 14-fold A2 selective compound, was modified by introduction of a variety of substituents in the benzene ring and the side chain.Some of these changes led to improved A2 affinity and increased selectivity.Replacement of the phenyl moiety by cyclohexenyl produced a 210-fold selective agonist 3ag (CGS 22989) whereas the cyclohexanyl analogue 3af (CGS 22492) was 530-fold selective at the A2 site.These compounds showed hypotensive activity in rat models over a range of doses without the bradycardia observed with less selective agonists.
