1354928-50-9

Basic information

• Product Name: N-((1S,4S,4aS,5R,6R,8aS)-5-amino-4-((2R,5S)-5-chloro-2,6,6-trimethyltetrahydro-2H-pyran-2-yl)-6-hydroxy-1,6-dimethyldecahydronaphthalen-1-yl)-4-methylbenzenesulfonamide
• Synonyms: N-((1S,4S,4aS,5R,6R,8aS)-5-amino-4-((2R,5S)-5-chloro-2,6,6-trimethyltetrahydro-2H-pyran-2-yl)-6-hydroxy-1,6-dimethyldecahydronaphthalen-1-yl)-4-methylbenzenesulfonamide
• CAS NO: 1354928-50-9
• Molecular Weight: 527.168
• Mol File: 1354928-50-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-((1S,4S,4aS,5R,6R,8aS)-5-amino-4-((2R,5S)-5-chloro-2,6,6-trimethyltetrahydro-2H-pyran-2-yl)-6-hydroxy-1,6-dimethyldecahydronaphthalen-1-yl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-((1S,4S,4aS,5R,6R,8aS)-5-amino-4-((2R,5S)-5-chloro-2,6,6-trimethyltetrahydro-2H-pyran-2-yl)-6-hydroxy-1,6-dimethyldecahydronaphthalen-1-yl)-4-methylbenzenesulfonamide(1354928-50-9)
• EPA Substance Registry System: N-((1S,4S,4aS,5R,6R,8aS)-5-amino-4-((2R,5S)-5-chloro-2,6,6-trimethyltetrahydro-2H-pyran-2-yl)-6-hydroxy-1,6-dimethyldecahydronaphthalen-1-yl)-4-methylbenzenesulfonamide(1354928-50-9)

Safety Data

• Hazardous Substances Data: 1354928-50-9(Hazardous Substances Data)

Upstream product

• 440333-53-9 (2S,5RS)-5-(tert-butyldimethylsilanyloxy)-2-[(2R,5S)-(5-chloro-2,6,6-trimethyltetrahydropyran-2-yl)]-6-hepten-1-ol 
• 440333-51-7 2,2-Dimethyl-propionic acid (S)-2-((2R,5S)-5-chloro-2,6,6-trimethyl-tetrahydro-pyran-2-yl)-5-hydroxy-hept-6-enyl ester 
• 440333-40-4 (4S,4aR,8aR)-4-((2R,5S)-5-chloro-2,6,6-trimethyltetrahydro-2H-pyran-2-yl)-6-methyl-3,4,4a,7,8,8a-hexahydronaphthalen-1-one 
• 440333-47-1 2,2-Dimethyl-propionic acid (S)-2-((2R,5S)-5-chloro-2,6,6-trimethyl-tetrahydro-pyran-2-yl)-5-hydroxy-pentyl ester 
• 440333-49-3 2,2-Dimethyl-propionic acid (S)-2-((2R,5S)-5-chloro-2,6,6-trimethyl-tetrahydro-pyran-2-yl)-5-oxo-pentyl ester 
• 158512-40-4 (E)-(R)-8-(tert-Butyl-dimethyl-silanyloxy)-2,6-dimethyl-octa-1,6-dien-3-ol 
• 440333-15-3 (2E,6R)-(+)-3,7-dimethyl-octa-2,7-diene-1,6-diol 
• 55962-05-5 [N-(p-tolylsulfonyl)imino]phenyliodinane 
• 440333-27-7 C₄₀H₅₄O₆Si 
• 440333-58-4 (2S,3R,6R)-2-{3-(benzyloxy)propyl}-6-(tert-butyldiphenylsilyloxy)-3,7-dimethyloct-7-ene-1,3-diol 
• 440333-17-5 (2R,3R,6R)-6-(tert-butyldiphenylsilanyloxy)-2,3-epoxy-3,7-dimethyloct-7-en-1-ol 
• 1354928-74-7 C₂₇H₄₁ClN₂O₄S 
• 1354928-48-5 (1'S,4'S,4a'S,5'R,6'R,8a'S)-5'-azido-4'-((2R,5S)-5-chloro-2,6,6-trimethyltetrahydro-2H-pyran-2-yl)-6'-methyl-1-tosyloctahydro-2'H-spiro[aziridine-2,1'-naphthalen]-6'-ol 
• 1354928-46-3 (1R,2R,4aS,8S,8aS)-1-azido-8-((2R,5S)-5-chloro-2,6,6-trimethyltetrahydro-2H-pyran-2-yl)-2-methyl-5-methylenedecahydronaphthalen-2-ol 

Downstream Products

• 91294-83-6 kalihinol-A 

Relevant articles and documents

Total synthesis of antimalarial diterpenoid (+)-kalihinol A

Total synthesis of antimalarial diterpenoid (+)-kalihinol A, isolated from marine sponge Acanthella sp., is achieved. This total synthesis involves regioselective alkylation of an epoxide, construction of a tetrahydropyran ring by iodo-etherification, construction of a cis-decalin ring by intramolecular Diels-Alder reaction, isomerization of cis-decalin to trans-decalin, and subsequent functionalization of the trans-decalin ring.