1355011-33-4

Basic information

• Product Name: 1,3-difluoro-5-(2-methoxyethoxy)benzene
• Synonyms: 1,3-difluoro-5-(2-methoxyethoxy)benzene
• CAS NO: 1355011-33-4
• Molecular Weight: 188.174
• Mol File: 1355011-33-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1,3-difluoro-5-(2-methoxyethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-difluoro-5-(2-methoxyethoxy)benzene(1355011-33-4)
• EPA Substance Registry System: 1,3-difluoro-5-(2-methoxyethoxy)benzene(1355011-33-4)

Safety Data

• Hazardous Substances Data: 1355011-33-4(Hazardous Substances Data)

Usage

Structure

Benzene derivative with two fluorine atoms at the 1 and 3 positions and a 2-methoxyethoxy group at the 5 position

Applications

a. Intermediate in the synthesis of pharmaceuticals and agrochemicals
b. Building block in organic synthesis for various chemical reactions
c. Potential applications in material science
d. Reagent in chemical research

Solubility

Relatively low solubility in water

Safety

Proper handling and storage necessary to prevent environmental contamination and ensure safety

Reactivity

Potential reactivity due to the presence of fluorine atoms and the 2-methoxyethoxy group

Upstream product

• 109-86-4 2-methoxy-ethanol 
• 2713-34-0 3,5-difluorophenol 

Downstream Products

• 1395282-76-4 3-amino-6-(2,6-difluoro-4-(2-methoxyethoxy)phenyl)-5-fluoropicolinic acid 
• 1395282-73-1 methyl 3-amino-6-(2,6-difluoro-4-(2-methoxyethoxy)phenyl)-5-fluoropicolinate 
• 1355011-36-7 6-(2,6-difluoro-4-(2-methoxyethoxy)phenyl)-5-fluoropicolinic acid 
• 1355011-35-6 methyl 6-(2,6-difluoro-4-(2-methoxyethoxy)phenyl)-5-fluoropicolinate 
• 1355011-34-5 2-(2,6-difluoro-4-(2-methoxyethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Relevant articles and documents

N-(3-PYRIDYL) BIARYLAMIDES AS KINASE INHIBITORS

The present invention provides a compound of formula (I): as described herein, and pharmaceutically acceptable salts, enantiomers, rotamers, tautomers, or racemates thereof. Also provided are methods of treating a disease or condition mediated by PIM kinase using the compounds of Formula (I), and pharmaceutical compositions comprising such compounds.

ARYL-SUBSTITUTED FUSED BICYCLIC PYRIDAZINE COMPOUNDS

The present invention provides a compound of formula (I) as described herein, and pharmaceutically acceptable salts, enantiomers, rotamers, tautomers, or racemates thereof. Also provided are methods of treating a disease or condition mediated by PIM kinase using the compounds of Formula (I), and pharmaceutical compositions comprising such compounds.

CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS

The present invention provides a compound of Formula (I): and pharmaceutically acceptable salts thereof, as further described herein. Also provided are formulations comprising compounds of formula I, and a method to use such compounds for treating a disease or condition mediated by Provirus Integration of Maloney Maloney Kinase (PIM Kinase), GSK3, PKC, KDR, PDGFRa, FGFR3, FLT3, or cABL.