1355052-60-6Relevant articles and documents
PYRIMIDINES AND USE THEREOF
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Page/Page column 61; 62, (2015/07/07)
The present disclosure provides pyrimidines of Formula I: and pharmaceutically acceptable salts and solvates thereof, wherein A1, X, A2, G, Y, n, R2a, R2b, and R3 are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula I and the pharmaceutically acceptable salts and solvates thereof to treat a disorder responsive to the blockade of one or more sodium channels. In one embodiment, compounds of the present disclosure are useful for treating pain.
TRIAZINE CARBOXAMIDES AS SODIUM CHANNEL BLOCKERS
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Paragraph 0285; 0286, (2014/09/16)
The present disclosure provides substituted triazine carboxamides of Formula I: and the pharmaceutically acceptable salts and solvates thereof, wherein A1, X, A2, E, and Z are defined as set forth in the specification. The present di
PYRIDINE COMPOUNDS AS SODIUM CHANNEL BLOCKERS
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Page/Page column 117, (2012/02/02)
The invention relates to substituted pyridine compounds of Formula I: (I) or a pharmaceutically acceptable salt, prodrug, or solvate thereof, wherein A1, X, A2, R1a, R1b, R1c, G, and z are defined as