1355235-84-5Relevant articles and documents
Mechanistic studies on regioselective dephosphorylation of phosphate prodrugs during a facile synthesis of antitumor phosphorylated 2-phenyl-6,7-methylenedioxy-1H-quinolin-4-one
Cheng, Yung-Yi,Liu, Chin-Yu,Huang, Li-Jiau,Huang, Chi-Hung,Lee, Kuo-Hsiung,Lin, Cheng-Tung,Kuo, Sheng-Chu
, p. 8028 - 8045 (2013/08/23)
Phosphorylation of 2-(3-hydroxy-5-methoxyphenyl)-6,7-methylenedioxy- 1Hquinolin- 4-one (1) afforded diphosphate 2. We found that, upon treatment with methanol under mild conditions, 2 can undergo facile and highly regioselective dephosphorylation to give