1355255-19-4Relevant articles and documents
ortho-Alkylation of Pyridine N-Oxides with Alkynes by Photocatalysis: Pyridine N-Oxide as a Redox Auxiliary
Markham, Jonathan P.,Wang, Ban,Stevens, Edwin D.,Burris, Stuart C.,Deng, Yongming
, p. 6638 - 6644 (2019)
A photocatalyzed ortho-alkylation of pyridine N-oxide with ynamides and arylacetylenes has been developed, which yields a series of α-(2-pyridinyl) benzyl amides/ketones. Mechanistic studies, including electrochemical studies, radical-trapping experiments, and Stern–Volmer fluorescence quenching studies demonstrate that pyridine N-oxide serves as both a redox auxiliary and radical acceptor to achieve the mild photocatalytic single-electron oxidation of carbon–carbon triple bonds with the generation of a cationic vinyl radical intermediate.
Catalytic asymmetric α-chlorination of 3-acyloxazolidin-2-one with a trinary catalytic system
Hamashima, Yoshitaka,Nagi, Tatsuya,Shimizu, Ryo,Tsuchimoto, Teruhisa,Sodeoka, Mikiko
supporting information; scheme or table, p. 3675 - 3678 (2011/09/15)
Direct asymmetric α-chlorination of aryl acetic acid derivatives was achieved with a novel trinary activation system consisting of a catalytic amount of NiCl2/(R)-BINAP, Et3SiOTf, and a tertiary amine base. The reaction smoothly affo
