1355677-37-0Relevant articles and documents
Synthesis and biological evaluation of novel pyrimidine derivatives as sub-micromolar affinity ligands of GalR2
Sagi, Vasudeva Naidu,Liu, Tianyu,Lu, Xiaoying,Bartfai, Tamas,Roberts, Edward
experimental part, p. 7210 - 7215 (2012/01/15)
GalR1 and GalR2 represent unique pharmacological targets for treatment of seizures and epilepsy. A novel series of 2,4,6-triaminopyrimidine derivatives were synthesized and found to have sub-micromolar affinity for GalR2. Optimization of a series of 2,4,6