135569-53-8

Basic information

• Product Name: 1-Naphthalenamine, N-[(4-chlorophenyl)methylene]-
• CAS NO: 135569-53-8
• Molecular Formula: C17H12ClN
• Molecular Weight: 265.742
• Mol File: 135569-53-8.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 1-Naphthalenamine, N-[(4-chlorophenyl)methylene]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Naphthalenamine, N-[(4-chlorophenyl)methylene]-(135569-53-8)
• EPA Substance Registry System: 1-Naphthalenamine, N-[(4-chlorophenyl)methylene]-(135569-53-8)

Safety Data

• Hazardous Substances Data: 135569-53-8(Hazardous Substances Data)

Usage

Common uses

Intermediate in the synthesis of various pharmaceuticals and organic compounds

Potential health effects

Mutagenic and carcinogenic

Physical form

Solid, crystalline substance

Color

White to off-white

Primary applications

Production of dyes, pigments, and other specialty chemicals

Usage

Mainly in research and development settings

Handling precautions

Should be handled with care due to potential health effects

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 134-32-7 1-amino-naphthalene 
• 873-76-7 para-Chlorobenzyl alcohol 

Downstream Products

• 1429117-81-6 6-(4-chlorophenyl)-11H-benzo[h]indolo[3,2-c]quinoline 
• 1335242-67-5 C₂₁H₁₅ClN₂ 
• 117358-61-9 10,10-dimethyl-7-(p-chlorophenyl)-7,10,11,12-tetrahydrobenzo[c]acridin-8(9H)-one 
• 135569-52-7 trans-4-(chlorophenyl)-3-methoxy-1-α-naphthyl-2-azetidinone 
• 135569-51-6 cis-4-(chlorophenyl)-3-methoxy-1-α-naphthyl-2-azetidinone 
• 135569-43-6 trans-1-α-naphthyl-3-(methylphenylamino)-4-(p-chlorophenyl)-2-azetidinone 

Relevant articles and documents

Imino Diels-Alder reactions: an efficient one-pot synthesis of pyrano and furanoquinoline derivatives catalyzed by SbCl3

Antimony trichloride (SbCl3) was found to be an efficient catalyst for the inverse electron demand imino Diels-Alder reactions of in situ generated N-benzylidenes with 3,4-dihydro-2H-pyran and 2,3-dihydrofuran to afford pyrano and furano[3,2-c]quinolines in excellent yields.

Analgesic, anti-inflammatory activity and docking study of 2-(substituted phenyl)-3-(naphthalen-1-yl)thiazolidin-4-ones

A potential analgesic and anti-inflammatory activities have been reported in 4-thiazolidinone analogs as well as some drugs bearing naphthyl moiety such as naproxen. Thus a reported series of 2-(substituted phenyl)-3-(naphthalen-1-yl)thiazolidin-4-ones (T

Stereoselective Synthesis of 3-(5-Benzoyl-1-methyl-1 H -pyrrol-2-yl)-2-azetidinone Derivatives via an in Situ Generated Ketene

A short route toward β-lactams from tolmetin has been developed. In the key step, a ketene was generated on the C-2 of pyrrole ring and reacted with aromatic imines to form trans -β-lactams as the only observed products. The identification of the ketene was confirmed by reaction with the stable free radical TEMPO (TO·).