1356546-23-0

Basic information

• Product Name: C₃₂H₄₉NO₂
• CAS NO: 1356546-23-0
• Molecular Weight: 479.747
• Mol File: 1356546-23-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₃₂H₄₉NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₂H₄₉NO₂(1356546-23-0)
• EPA Substance Registry System: C₃₂H₄₉NO₂(1356546-23-0)

Safety Data

• Hazardous Substances Data: 1356546-23-0(Hazardous Substances Data)

Upstream product

• 1279699-92-1 (S)-3-(dibenzylamino)-1-[(R)-p-tolylsulfinyl]butan-2-one 
• 1279699-93-2 (2R,3S)-3-(dibenzylamino)-1-[(R)-p-tolylsulfinyl]butan-2-ol 
• 1356546-26-3 2-(tetradecan-2-ylidene)-1,1-dimethylhydrazine 
• 127927-42-8 (2R)-[(1S)-1-(dibenzylamino)ethyl]oxirane 
• 103-49-1 dibenzylamine 

Relevant articles and documents

A route to "all-cis" 2-methyl-6-substituted piperidin-3-ol alkaloids from syn-(2R,1′S)-2-(1-dibenzylaminomethyl)epoxide: Rapid total synthesis of (+)-deoxocassine

A general strategy leading to the synthesis of two cis-2-methyl-6- substituted piperidin-3-ols is described. syn-(2R,1′S)-2-(1- Dibenzylaminomethyl) epoxide (13) was used as common building block. The key step involved oxirane ring opening of 13 by the nucleophilic lithium aza-enolate of hydrazones 12a and 12b. Subsequent hydrazone hydrolysis and intramolecular reductive amination afforded the alkaloid (+)-deoxocassine and a new C-6 ethyl analogue of this substance in good yields.