1356550-80-5Relevant articles and documents
Antiproliferative activity of Pt(IV) complexes with lonidamine and bexarotene ligands attached via succinate-ethylenediamine linker
Okulova,Zenin,Shutkov,Kirsanov,Kovaleva,Lesovaya,Fetisov,Milaeva,Nazarov
, (2019)
We present the synthesis and cytotoxic potencies of new Pt(IV) complexes with lonidamine and bexarotene ligand tethered to Pt-center via a succinate-ethylenediamine linker. The in vitro results for a series of complexes with cisplatin, dichloride(ethane-1,2-diamine)platinum(II), or oxaliplatin core indicate that the addition to the structure lonidamine or bexarotene moiety can confer activity or selectivity of Pt(IV) complexes.