135661-44-8 Usage
Description
Sulfosuccinimidyl Oleate Sodium is a long-chain fatty acid derivative characterized by its off-white solid appearance. It possesses unique chemical properties that enable it to interact with various biological systems, making it a versatile compound with potential applications in different industries.
Uses
Used in Pharmaceutical Industry:
Sulfosuccinimidyl Oleate Sodium is used as an inhibitor for the inhibition of fatty acid transport. Its ability to interfere with the transport of fatty acids can be utilized in the development of drugs targeting metabolic disorders and conditions related to lipid metabolism.
Used in Biochemical Research:
In the field of biochemical research, Sulfosuccinimidyl Oleate Sodium serves as a valuable tool for studying the role of fatty acid transport in cellular processes. It can be employed to investigate the mechanisms underlying fatty acid metabolism and its regulation, contributing to a better understanding of various diseases and conditions associated with lipid metabolism.
Used in Drug Delivery Systems:
Sulfosuccinimidyl Oleate Sodium can be used as a component in the development of drug delivery systems, particularly for drugs targeting metabolic disorders. Its ability to inhibit fatty acid transport can be leveraged to improve the efficacy and specificity of drug delivery, potentially enhancing the therapeutic outcomes for patients.
Used in Cosmetics Industry:
In the cosmetics industry, Sulfosuccinimidyl Oleate Sodium may find applications in the development of products aimed at addressing skin conditions related to lipid metabolism, such as acne or seborrhea. Its ability to inhibit fatty acid transport could be utilized to create formulations that help regulate sebum production and maintain skin health.
Check Digit Verification of cas no
The CAS Registry Mumber 135661-44-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,6,6 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 135661-44:
(8*1)+(7*3)+(6*5)+(5*6)+(4*6)+(3*1)+(2*4)+(1*4)=128
128 % 10 = 8
So 135661-44-8 is a valid CAS Registry Number.
InChI:InChI=1/C22H37NO7S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(25)30-23-20(24)18-19(22(23)26)31(27,28)29/h9-10,19H,2-8,11-18H2,1H3,(H,27,28,29)/b10-9-
135661-44-8Relevant articles and documents
Trans-membrane uptake and intracellular metabolism of fatty acids in Atlantic salmon (Salmo salar L.) hepatocytes
Zhou, Jishu,Stubhaug, Ingunn,Torstensen, Bente E.
experimental part, p. 301 - 311 (2010/10/18)
To elucidate if the trans-membrane uptake of fatty acids is protein-mediated, the uptake of oleic acid (18:1n-9), linoleic acid (18:2n-6), alpha-linolenic acid (18:3n-3), eicosapentaenoic acid (20:5n-3) and docosahexaenoic acid (22:6n-3) was investigated in vitro in Atlantic salmon (Salmo salar L.) primary hepatocytes. Firstly, optimal fatty acid incubation time and concentration were established for trans-membrane 18:n-9 uptake. Based on saturation kinetics, a 2-h incubation time and 37.5 μM were used for the following experiments. Secondly, in order to identify whether trans-membrane fatty acid uptake in hepatocytes was mainly passive or protein mediated, hepatocytes were pre-incubated with membrane protein inhibitors followed by 2 h of incubation with [1-14C] labelled 18:1n-9, 18:2n-6, 18:3n-3, 20:5n-3 and 22:6n-3. Fatty acid uptake into hepatocytes was highest with 20:5n-3 and 22:6n-3 and lowest with 18:1n-9. Phloretin was the most potent fatty acid uptake inhibitor, inhibiting uptake in the following order: 20:5n-3>18:3n-3 = 22:6n-3>18:2n-6>18:1n-9. The uptake of FA in Atlantic salmon hepatocytes seem to be due to both saturable and inhibitable protein mediated uptake, as well as passive uptake processes with more unsaturated and long fatty acids (20:n- 3>22:6n-3 = 18:3n-3>18:2n-6) beingmore dependent on membrane protein mediated uptake compared to 18:1n-9. AOCS 2010.
