1357024-62-4Relevant articles and documents
Pyrrole alkanoic acid derivatives as nuisance inhibitors of microsomal prostaglandin E2 synthase-1
Wiegard, Andrea,Hanekamp, Walburga,Griessbach, Klaus,Fabian, J?rg,Lehr, Matthias
supporting information; experimental part, p. 153 - 163 (2012/03/26)
Microsomal prostaglandin E2 synthase-1 (mPGES-1) is an enzyme, which is induced during the inflammatory response. Therefore, inhibitors of this enzyme are considered to be potential anti-inflammatory drugs. We have identified 3-(4-dodecanoyl-1,