1357111-55-7

Basic information

• Product Name: 4-chloro-6-[1-(2-hydroxyethyl)-5-nitro-1H-benzimidazol-2-yl]benzene-1,3-diol
• CAS NO: 1357111-55-7
• Molecular Weight: 349.73
• Mol File: 1357111-55-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-chloro-6-[1-(2-hydroxyethyl)-5-nitro-1H-benzimidazol-2-yl]benzene-1,3-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-6-[1-(2-hydroxyethyl)-5-nitro-1H-benzimidazol-2-yl]benzene-1,3-diol(1357111-55-7)
• EPA Substance Registry System: 4-chloro-6-[1-(2-hydroxyethyl)-5-nitro-1H-benzimidazol-2-yl]benzene-1,3-diol(1357111-55-7)

Safety Data

• Hazardous Substances Data: 1357111-55-7(Hazardous Substances Data)

Upstream product

• 56932-44-6 1-(2'-hydroxy-ethyl)amino-2-amino-4-nitro-benzene 
• 1298083-50-7 bis[(5-chloro-2,4-dihydroxyphenyl)methanethione]sulfoxide 

Relevant articles and documents

Synthesis and biological activity of novel 4- and 6-(1-alkyl/aryl-1H- benzimidazol-2-yl)benzene-1,3-diols

A one-pot synthesis of new biologically active 4- and 6-(1-alkyl/aryl-17/- benzimidazol-2-yl)benzene-1,3-diols has been developed. The compounds were obtained by the reaction of aryl-modified sulfinylbis[(2,4-dihy-droxyphenyl) methanethione] with N-substituted benzene-1,2-diamines. Elemental analysis, IR, 1H NMR, 13C NMR, and mass spectral data were used to elucidate their structures. The developed method offers short reaction times, easy and quick isolation of the products, and good yields. The antiproliferative properties of the synthesized compounds were investigated against a panel of human cancer cell lines. Some of the tested compounds showed significant cytotoxic activity.