1357113-62-2

Basic information

• Product Name: 3-(2-(4-isobutylphenyl)propanoyl)-1-methylimidazolidine-2,4-dione
• CAS NO: 1357113-62-2
• Molecular Weight: 302.373
• Mol File: 1357113-62-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2-(4-isobutylphenyl)propanoyl)-1-methylimidazolidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-(4-isobutylphenyl)propanoyl)-1-methylimidazolidine-2,4-dione(1357113-62-2)
• EPA Substance Registry System: 3-(2-(4-isobutylphenyl)propanoyl)-1-methylimidazolidine-2,4-dione(1357113-62-2)

Safety Data

• Hazardous Substances Data: 1357113-62-2(Hazardous Substances Data)

Upstream product

• 616-04-6 1-methyldiazolidine-2,4-dione 
• 71381-91-4 (+/-)-2-(4-isobutylphenyl)propanoyl chloride 

Relevant articles and documents

Synthesis and evaluation of anti-inflammatory and antitussive activity of hydantion derivatives

1-Methylhydantion is a compound, which was isolated from Oviductus Ranae for the first time. In our study, we found that it showed good antitussive and anti-inflammatory activity. It is also the first report which illustrates the antitussive activity of hydantion derivative. A series of hydantion derivatives were synthesized and evaluated for their anti-inflammatory and antitussive activity in vivo. The pharmacological tests showed that compounds 7a, 7c and 7d have good anti-inflammatory and antitussive activity compared to Ibuprofen and codeine. Compound 7a in particular showed two-fold stronger anti-inflammatory activity than Ibuprofen.