1357309-74-0Relevant articles and documents
Protein enrichment by capture-release based on strain-promoted cycloaddition of azide with bicyclononyne (BCN)
Temming, Rinske P.,Van Scherpenzeel, Monique,Te Brinke, Esra,Schoffelen, Sanne,Gloerich, Jolein,Lefeber, Dirk J.,Van Delft, Floris L.
, p. 655 - 661 (2012/03/11)
An enrichment strategy was devised for azide derivatized macromolecules, based on strain-promoted alkyne-azide cycloaddition (SPAAC) and a cleavable linker. A ring-strained alkyne, bicyclo[6.1.0]non-4-yne (BCN), was covalently attached to agarose beads vi