1357519-11-9

Basic information

• Product Name: 1-(2-chloroallylsulfinyl)-4-methylbenzene
• Synonyms: 1-(2-chloroallylsulfinyl)-4-methylbenzene
• CAS NO: 1357519-11-9
• Molecular Weight: 214.716
• Mol File: 1357519-11-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(2-chloroallylsulfinyl)-4-methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-chloroallylsulfinyl)-4-methylbenzene(1357519-11-9)
• EPA Substance Registry System: 1-(2-chloroallylsulfinyl)-4-methylbenzene(1357519-11-9)

Safety Data

• Hazardous Substances Data: 1357519-11-9(Hazardous Substances Data)

Upstream product

• 4860-96-2 3-bromo-2-chloroprop-1-ene 
• 106-45-6 para-thiocresol 
• 53299-60-8 1-[(2-chloro-2-propen-1-yl)thio]-4-methylbenzene 

Relevant articles and documents

Aryne 1,2,3,5-Tetrasubstitution Enabled by 3-Silylaryne and Allyl Sulfoxide via an Aromatic 1,3-Silyl Migration

Although benzyne has been well-known to serve as a synthon that can conveniently prepare various 1,2-difunctionalized benzenes, the sites other than its formal triple bond remain silent in typical benzyne transformations. An unprecedented aryne 1,2,3,5-tetrasubstitution was realized from 3-silylbenzyne and aryl allyl sulfoxide, the mechanistic pathway of which includes a regioselective aryne insertion into the SO bond, a [3,6]-sigmatropic rearrangement, and a thermal aromatic 1,3-silyl migration cascade.

Highly chemoselective synthesis of aryl allylic sulfoxides through calcium hypobromite oxidation of aryl allylic sulfides

A highly chemoselective oxidation of widely substituted aryl allylic sulfides, prepared by allylation of arylthioethers with KF-Celite, to the corresponding aryl allylic sulfoxide was achieved by employing calcium hypobromite. Neither over-oxidation to sulfones nor halogenation of the aromatic rings was observed. The protocol may be successfully applied for the oxidation of substituted allylic systems (i.e., 2-haloallyl) that per se could interact with the oxidizing agent.