1357570-21-8

Basic information

• Product Name: Ramipril Acyl--D-glucuronide, ~ 80% By HPLC
• Synonyms: Ramipril Acyl--D-glucuronide, ~ 80% By HPLC;1-[(2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]aMino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylate] β-D-Glucopyranuronic Acid;Ramipril-acyl-beta-D-glucuronide min. 95%;RaMipril Acyl-β-D-glucuronide
• CAS NO: 1357570-21-8
• Molecular Formula: C29H40N2O11
• Molecular Weight: 592.6347
• Product Categories: Glucuronides;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 1357570-21-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 128-130°C
• Appearance: /
• Storage Temp.: Hygroscopic, Store under Inert atmosphere -20°C Freezer
• Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
• CAS DataBase Reference: Ramipril Acyl--D-glucuronide, ~ 80% By HPLC(CAS DataBase Reference)
• NIST Chemistry Reference: Ramipril Acyl--D-glucuronide, ~ 80% By HPLC(1357570-21-8)
• EPA Substance Registry System: Ramipril Acyl--D-glucuronide, ~ 80% By HPLC(1357570-21-8)

Safety Data

• Hazardous Substances Data: 1357570-21-8(Hazardous Substances Data)

Usage

Description

Ramipril Acyl--D-glucuronide, ~ 80% By HPLC is a metabolite of Ramipril, an angiotensin-converting enzyme (ACE) inhibitor commonly used in the treatment of hypertension and heart failure. It is a pale yellow solid that is not stable in an aqueous solution.

Uses

Used in Pharmaceutical Industry:
Ramipril Acyl--D-glucuronide, ~ 80% By HPLC is used as an intermediate in the synthesis of pharmaceutical compounds for the treatment of hypertension and heart failure. As a metabolite of Ramipril, it plays a role in the drug's therapeutic effects and helps researchers understand the drug's metabolism and pharmacokinetics.
Used in Research and Development:
Ramipril Acyl--D-glucuronide, ~ 80% By HPLC is used as a research compound for studying the metabolic pathways of ACE inhibitors and their effects on various physiological processes. This information can be valuable for the development of new drugs with improved efficacy and safety profiles.
Used in Quality Control:
Ramipril Acyl--D-glucuronide, ~ 80% By HPLC is used as a reference standard in the quality control of pharmaceutical products containing Ramipril. It helps ensure the accuracy and reliability of analytical methods used to determine the drug's concentration in various formulations.
Used in Drug Metabolism Studies:
Ramipril Acyl--D-glucuronide, ~ 80% By HPLC is used as a model compound in drug metabolism studies, providing insights into the metabolic pathways and enzyme interactions of ACE inhibitors. This information can be useful for predicting potential drug-drug interactions and optimizing drug dosing regimens.