13578-61-5 Usage
Description
1-(2-hydroxyethyl)-3-[3-(trifluoromethyl)phenyl]thiourea is a chemical compound with the molecular formula C10H12F3N3OS. It is a thiourea derivative that contains a hydroxyethyl group and a trifluoromethylphenyl group. 1-(2-hydroxyethyl)-3-[3-(trifluoromethyl)phenyl]thiourea has been found to exhibit various biological activities, such as antiviral, anticancer, and antidiabetic properties. The presence of the trifluoromethyl group on the phenyl ring significantly influences the compound's physicochemical and biological properties, making it a promising candidate for applications in medicinal chemistry and pharmaceutical research.
Uses
Used in Pharmaceutical Research:
1-(2-hydroxyethyl)-3-[3-(trifluoromethyl)phenyl]thiourea is used as a research compound for its potential antiviral, anticancer, and antidiabetic properties. 1-(2-hydroxyethyl)-3-[3-(trifluoromethyl)phenyl]thiourea's unique structure, including the hydroxyethyl and trifluoromethylphenyl groups, allows for investigation into its interactions with biological targets and its potential as a therapeutic agent.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(2-hydroxyethyl)-3-[3-(trifluoromethyl)phenyl]thiourea is used as a starting material or a structural motif for the development of new drugs. Its diverse biological activities and the ability to modify its structure make it a valuable tool for designing novel therapeutic agents targeting various diseases.
Used in Drug Design and Optimization:
1-(2-hydroxyethyl)-3-[3-(trifluoromethyl)phenyl]thiourea is used as a lead compound in drug design and optimization processes. Its unique structural features can be exploited to improve the potency, selectivity, and pharmacokinetic properties of potential drug candidates, ultimately leading to more effective treatments for various medical conditions.
Used in Chemical Synthesis:
This thiourea derivative can also be used as a synthetic building block or intermediate in the preparation of more complex molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 13578-61-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,5,7 and 8 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 13578-61:
(7*1)+(6*3)+(5*5)+(4*7)+(3*8)+(2*6)+(1*1)=115
115 % 10 = 5
So 13578-61-5 is a valid CAS Registry Number.
13578-61-5Relevant articles and documents
1-Hydroxyalkyl-3-phenylthioureas as novel HDL-elevating agents
Coppola, Gary M.,Damon, Robert E.,Eskesen, J. Bruce,France, Dennis S.,Paterniti Jr., James R.
, p. 809 - 812 (2007/10/03)
A series of 1-hydroxyalkyl-3-phenylthiourea analogs were prepared and evaluated as HDL-and Apo A-I-elevating agents. Derivatives 5h, 7j, 7n, and 7o were found to be as effective or superior to gemfibrozil (1).
