135780-99-3

Basic information

• Product Name: C₁₈H₂₀O₂
• CAS NO: 135780-99-3
• Molecular Weight: 268.356
• Mol File: 135780-99-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₀O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₀O₂(135780-99-3)
• EPA Substance Registry System: C₁₈H₂₀O₂(135780-99-3)

Safety Data

• Hazardous Substances Data: 135780-99-3(Hazardous Substances Data)

Upstream product

• 106-41-2 4-bromo-phenol 
• 10031-82-0 4-ethoxybenzaldehyde 
• 23676-09-7 ethyl 4-ethoxybenzoate 

Relevant articles and documents

Structurally-unusual calix[4]arene derivatives generated by intra-and intermolecular McMurry reactions

A new class of calix[4]arene derivatives with highly strained structures has been synthesized by intramolecular reductive dimerization of appropriate formyl groups in the presence of low-valent titanium agents (so-called McMurry reaction). New derivatives possessed very interesting molecular structures with upper rims intramolecularly connected by a CH=CH bond and are immobilized either in cone or in 1,3-alternate conformation. The cage compound with inner space perfectly closed by four aromatic units has been obtained from a tetraformyl derivative in 1,3-alternate conformation. Intermolecular reductive coupling of two monoformylcalix[4]arenes has yielded a bis-calixarene derivative which was found to behave as a good host molecule for quaternary ammonium salts.

REDUCTIVE COUPLING OF BENZOIC ACID HALIDES AND ESTERS USING LOW-VALENT TITANIUM

The reductive coupling of (substituted) benzoic acid chlorides and esters is achieved using low-valent titanium, generated from TiCl3 and LiAlH4.Both acid chlorides and esters seem to follow the same two reaction pathways: one path via tolanes to stilbenes, the other via benzils to complex mixtures of products arising from reduction and further coupling reactions.Although the exact product balance depends upon the reaction conditions the major product is (substituted) cis-stilbene.