135859-37-9

Basic information

• Product Name: (3R)- 4,4,4-trifluoro-1-(4-methylbenzenesulfonate)-1,3-Butanediol
• Synonyms: (3R)- 4,4,4-trifluoro-1-(4-methylbenzenesulfonate)-1,3-Butanediol
• CAS NO: 135859-37-9
• Molecular Formula: C11H13F3O4S
• Molecular Weight: 298.28
• Mol File: 135859-37-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3R)- 4,4,4-trifluoro-1-(4-methylbenzenesulfonate)-1,3-Butanediol(CAS DataBase Reference)
• NIST Chemistry Reference: (3R)- 4,4,4-trifluoro-1-(4-methylbenzenesulfonate)-1,3-Butanediol(135859-37-9)
• EPA Substance Registry System: (3R)- 4,4,4-trifluoro-1-(4-methylbenzenesulfonate)-1,3-Butanediol(135859-37-9)

Safety Data

• Hazardous Substances Data: 135859-37-9(Hazardous Substances Data)

Usage

General Description

The chemical (3R)-4,4,4-trifluoro-1-(4-methylbenzenesulfonate)-1,3-butane diol is a fluorinated compound that also contains a butane diol moiety and a sulfonate group. It has a chiral center, with the (3R) configuration indicating that the highest priority substituent is on the right side of the molecule. This chemical may be used in organic synthesis as a building block for constructing more complex molecules. The presence of the trifluoro and sulfonate groups may give it specific reactivity and properties that make it useful in certain reactions or as a starting material for pharmaceutical compounds or other fine chemicals. Its precise applications and uses would depend on its specific properties and how it is utilized in various chemical reactions.

Upstream product

• 433-25-0 (±)-4,4,4-trifluorobutane-1,3-diol 
• 98-59-9 p-toluenesulfonyl chloride 
• 433-25-0 (R)-4,4,4-trifluorobutane-1,3-diol 

Downstream Products

• 121170-45-4 (2R)-1,1,1-trifluorooctan-2-ol 

Relevant articles and documents

SYNTHESE DE LA TRIFLUOROMETHYL-VINYL-CETONE

The synthesis of trifluoromethylvinylketone 6 is described.The metal hydride reduction of ethyl trifluoroacetoacetate 1 gives the glycol 2.Selective tosylation of 2 occurs on the primary hydroxyl group and leads to 3.Tosyl-chloride exchange produces the c

Nucleophilic trifluoromethylation of conjugate acceptors via phenyl trifluoromethyl sulfone

A mild procedure for the conjugate addition of the trifluoromethyl anion to activated Michael acceptors such as arylidenemalononitriles (15 examples) and arylidene Meldrum's acids (9 examples) using phenyl trifluoromethyl sulfone through a reductive magnesium metal mediated procedure is described. The new methodology is used to prepare befloxatone, a reversible and selective monoamine oxidase A inhibitor.

Synthesis and Spin-Trapping Chemistry of 5,5-Dimethyl-2-(trifluoromethyl)-1-pyrroline N-Oxide

A new five-membered ring nitrone, 5,5-dimethyl-2-(trifluoromethyl)-1-pyrroline N-oxide (2-TFDMPO), is synthesized for the purpose of spin trapping in free radical biology.Most of the spin adducts of 2-TFDMPO are persistent, and EPR, ENDOR, and MS spectra can be obtained.A variety of radicals give characteristic spectral signatures, among which is a rare type of line width alternation pattern due to hindered rotation of the trifluoromethyl group.