135882-37-0 Usage
Core Structure
Pyrroloquinoline
The central structure of the compound, consisting of two fused five-membered rings with one nitrogen atom in the pyrrole ring and two nitrogen atoms in the quinoline ring.
Attached Groups
Benzyl group and amine functional group
The benzyl group is a phenyl ring attached to a methylene group (-CH2-), contributing to the compound's hydrophobicity and potential pharmacokinetic properties.
The amine functional group (-NH2) is a basic group that can participate in hydrogen bonding and ionic interactions, which may contribute to the compound's pharmacological activity and solubility.
Heterocyclic Compound
Yes
Contains at least one ring structure with at least one non-carbon atom (e.g., nitrogen) in the ring.
Potential Therapeutic Applications
Various diseases and disorders
The compound has been studied for its potential use in drug development, targeting a range of medical conditions.
Biological Activities
Promising
Research has shown that 1-Benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-ylamine exhibits potentially useful biological activities, warranting further investigation.
Medicinal Chemistry Research
Interesting target
The unique structure and properties of the compound make it an attractive subject for further study in the field of medicinal chemistry.
Pharmacological Effects and Applications
Under investigation
Ongoing research is focused on understanding the potential pharmacological effects of the compound and its possible applications in the treatment of various diseases and disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 135882-37-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,8,8 and 2 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 135882-37:
(8*1)+(7*3)+(6*5)+(5*8)+(4*8)+(3*2)+(2*3)+(1*7)=150
150 % 10 = 0
So 135882-37-0 is a valid CAS Registry Number.
135882-37-0Relevant articles and documents
Synthesis and Evaluation of Dihydropyrroloquinolines That Selectively Antagonize P-Glycoprotein
Lee, Brian D.,Li, Zhanjiang,French, Kevin J.,Zhuang, Yan,Xia, Zuping,Smith, Charles D.
, p. 1413 - 1422 (2007/10/03)
In a search for improved multiple drug resistance (MDR) modulators, we identified a novel series of substituted pyrroloquinolines that selectively inhibits the function of P-glycoprotein (Pgp) without modulating multidrug resistance-related protein 1 (MRP
