135883-16-8 Usage
Uses
Used in Pharmaceutical Industry:
(3aR,12bR)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepin[4,5-c]pyrrole maleate is used as a pharmaceutical intermediate for the development of medications targeting the central nervous system. Its potential use as an antidepressant and antipsychotic stems from its impact on neurotransmitters and its ability to modulate serotonin and dopamine receptor activity.
Used in Neurological Disorder Treatment:
(3aR,12bR)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepin[4,5-c]pyrrole maleate is used in the research and development of treatments for neurological disorders due to its significant binding affinity for certain serotonin and dopamine receptors. Its potential applications in this area are currently under investigation, with the aim of developing new therapies for conditions such as depression, anxiety, and other mood disorders.
Used in Chronic Pain Management:
(3aR,12bR)-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepin[4,5-c]pyrrole maleate is also being explored for its potential in treating chronic pain conditions. Its ability to modulate neurotransmitter activity may contribute to the development of new pain management therapies, offering alternative treatment options for patients suffering from chronic pain.
Check Digit Verification of cas no
The CAS Registry Mumber 135883-16-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,8,8 and 3 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 135883-16:
(8*1)+(7*3)+(6*5)+(5*8)+(4*8)+(3*3)+(2*1)+(1*6)=148
148 % 10 = 8
So 135883-16-8 is a valid CAS Registry Number.
135883-16-8Relevant articles and documents
A method for the preparation of asenapine
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Paragraph 0025-0027, (2017/02/09)
The invention relates to a preparation method of a psychotropic medicine asenapine. The method comprises a step that asenapine is prepared through a reaction of a raw material trans-5-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-monobenzo[2,3:6,7]oxepino[4,5-C]pyrrole-1-one or trans-11-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenzo[2,3:6,7]oxepino[4,5-C]pyrrole-1-one under the action of a reducing agent sodium bisaluminumhydride or a composite reducing agent composed of sodium bisaluminumhydride and other regents. The method has the advantages of mild and controllable reaction technology, low production cost, good product yield, realization of the large scale application in the industrial production, and good enforcement values and social and economic benefits.
