1359020-96-4

Basic information

• Product Name: (E,Z)-1-benzyl-3-((5-(1-oxo-1,3-dihydroisobenzofuran-5-yl)thiophen-2-yl)methylene)pyrrolidin-2-one
• Synonyms: (E,Z)-1-benzyl-3-((5-(1-oxo-1,3-dihydroisobenzofuran-5-yl)thiophen-2-yl)methylene)pyrrolidin-2-one
• CAS NO: 1359020-96-4
• Molecular Weight: 401.486
• Mol File: 1359020-96-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E,Z)-1-benzyl-3-((5-(1-oxo-1,3-dihydroisobenzofuran-5-yl)thiophen-2-yl)methylene)pyrrolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E,Z)-1-benzyl-3-((5-(1-oxo-1,3-dihydroisobenzofuran-5-yl)thiophen-2-yl)methylene)pyrrolidin-2-one(1359020-96-4)
• EPA Substance Registry System: (E,Z)-1-benzyl-3-((5-(1-oxo-1,3-dihydroisobenzofuran-5-yl)thiophen-2-yl)methylene)pyrrolidin-2-one(1359020-96-4)

Safety Data

• Hazardous Substances Data: 1359020-96-4(Hazardous Substances Data)

Upstream product

• 52157-62-7 2-(5-bromothiophen-2-yl)-1,3-dioxolane 
• 1313397-92-0 5-(1-oxo-1,3-dihydroisobenzofuran-5-yl)thiophene-2-carbaldehyde 
• 643754-23-8 diethyl 1-(benzyl)-2-oxopyrrolidin-3-ylphosphonate 
• 1313397-91-9 5-(5-(1,3-dioxolan-2-yl)thiophen-2-yl)isobenzofuran-1(3H)-one 
• 862081-37-6 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isobenzofuran-1(3H)-one 

Relevant articles and documents

Inhibition of the pore-forming protein perforin by a series of aryl-substituted isobenzofuran-1(3H)-ones

An aryl-substituted isobenzofuran-1(3H)-one lead compound was identified from a high throughput screen designed to find inhibitors of the lymphocyte pore-forming protein perforin. A series of analogs were then designed and prepared, exploring structure-ac