135965-95-6

Basic information

• Product Name: (2S,3S)-2-((4S,5R)-4-Benzo[1,3]dioxol-5-yl-2,2-di-tert-butyl-[1,3,2]dioxasilinan-5-yl)-3-(1-ethoxy-ethoxy)-3-(3,4,5-trimethoxy-phenyl)-propionic acid methyl ester
• CAS NO: 135965-95-6
• Molecular Weight: 676.877
• Mol File: 135965-95-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3S)-2-((4S,5R)-4-Benzo[1,3]dioxol-5-yl-2,2-di-tert-butyl-[1,3,2]dioxasilinan-5-yl)-3-(1-ethoxy-ethoxy)-3-(3,4,5-trimethoxy-phenyl)-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-2-((4S,5R)-4-Benzo[1,3]dioxol-5-yl-2,2-di-tert-butyl-[1,3,2]dioxasilinan-5-yl)-3-(1-ethoxy-ethoxy)-3-(3,4,5-trimethoxy-phenyl)-propionic acid methyl ester(135965-95-6)
• EPA Substance Registry System: (2S,3S)-2-((4S,5R)-4-Benzo[1,3]dioxol-5-yl-2,2-di-tert-butyl-[1,3,2]dioxasilinan-5-yl)-3-(1-ethoxy-ethoxy)-3-(3,4,5-trimethoxy-phenyl)-propionic acid methyl ester(135965-95-6)

Safety Data

• Hazardous Substances Data: 135965-95-6(Hazardous Substances Data)

Upstream product

• 136031-31-7 (3S,4R)-4-(2-Benzo[1,3]dioxol-5-yl-[1,3]dithian-2-yl)-3-[(S)-hydroxy-(3,4,5-trimethoxy-phenyl)-methyl]-dihydro-furan-2-one 
• 135965-94-5 (3S,4R)-4-(Benzo[1,3]dioxole-5-carbonyl)-3-[(S)-(1-ethoxy-ethoxy)-(3,4,5-trimethoxy-phenyl)-methyl]-dihydro-furan-2-one 
• 135965-89-8 (3S,4R)-4-((S)-Benzo[1,3]dioxol-5-yl-hydroxy-methyl)-3-[(S)-(1-ethoxy-ethoxy)-(3,4,5-trimethoxy-phenyl)-methyl]-dihydro-furan-2-one 
• 135965-93-4 (3S,4R)-4-(Benzo[1,3]dioxole-5-carbonyl)-3-[(S)-hydroxy-(3,4,5-trimethoxy-phenyl)-methyl]-dihydro-furan-2-one 
• 85272-31-7 di-tert-butylsilyl bis(trifluoromethanesulfonate) 

Downstream Products

• 136031-37-3 (4aR,5R,6R,11bS)-2,2-Di-tert-butyl-6-(3,4,5-trimethoxy-phenyl)-4a,5,6,11b-tetrahydro-4H-1,3,8,10-tetraoxa-2-sila-cyclopenta[b]phenanthrene-5-carboxylic acid methyl ester 
• 4375-07-9 epipodophyllotoxin 
• 136031-36-2 (2S,3S)-2-((4S,5R)-4-Benzo[1,3]dioxol-5-yl-2,2-di-tert-butyl-[1,3,2]dioxasilinan-5-yl)-3-hydroxy-3-(3,4,5-trimethoxy-phenyl)-propionic acid methyl ester 

Relevant articles and documents

Enantioselective Total Synthesis of (-)-Epipodophyllotoxin and (-)-Podophyllotoxin

An enantioselective total synthesis of (-)-epipodophyllotoxin (2) and hence of (-)-podophyllotoxin (1) is described, involving as key steps a conjugate addition on butenolide 13 as the chiral template, a stereoselective aldol condensation on 11a and a ste