135984-50-8

Basic information

• Product Name: 1,4-Diethyl-3,5-dimethoxy-cyclohexa-2,5-dienecarboxylic acid methyl ester
• CAS NO: 135984-50-8
• Molecular Weight: 254.326
• Mol File: 135984-50-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,4-Diethyl-3,5-dimethoxy-cyclohexa-2,5-dienecarboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Diethyl-3,5-dimethoxy-cyclohexa-2,5-dienecarboxylic acid methyl ester(135984-50-8)
• EPA Substance Registry System: 1,4-Diethyl-3,5-dimethoxy-cyclohexa-2,5-dienecarboxylic acid methyl ester(135984-50-8)

Safety Data

• Hazardous Substances Data: 135984-50-8(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 74-96-4 ethyl bromide 
• 1132-21-4 3,5-dimethoxybenzoic acid 

Downstream Products

• 78612-88-1 5-(2-Bromo-1-ethoxy-ethoxymethyl)-2,5-diethyl-3-methoxy-cyclohex-2-enone 
• 78612-87-0 2,5-Diethyl-5-hydroxymethyl-3-methoxy-cyclohex-2-enone 
• 78612-86-9 (1,4-Diethyl-3,5-dimethoxy-cyclohexa-2,5-dienyl)-methanol 

Relevant articles and documents

The Birch reduction - Dialkylation reaction of aromatic carboxylic acids. Identification of NaNH2 as the base responsible for the second alkylation

The Birch reduction-alkylation of 3,5-dimethoxybenzoic acid with excesses Na and EDtBr gives 1,4-diethyl-3,5-dimethoxy-2,5-cyclohexadiene carboxylic acid, 3. The base responsible for the alkylation at C-4 has been identified as NaNH2, generated