1360467-58-8

Basic information

• Product Name: 4-methylbenzenesulfinic acid 1,1,3,3-tetramethylguanidine salt
• CAS NO: 1360467-58-8
• Molecular Weight: 271.384
• Mol File: 1360467-58-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-methylbenzenesulfinic acid 1,1,3,3-tetramethylguanidine salt(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methylbenzenesulfinic acid 1,1,3,3-tetramethylguanidine salt(1360467-58-8)
• EPA Substance Registry System: 4-methylbenzenesulfinic acid 1,1,3,3-tetramethylguanidine salt(1360467-58-8)

Safety Data

• Hazardous Substances Data: 1360467-58-8(Hazardous Substances Data)

Upstream product

• 14062-05-6 N,N'-ditosylhydrazine 
• 887571-06-4 2-bromo-1-(1,1-dioxidothiomorpholino)ethanone 
• 80-70-6 N,N,N',N'-tetramethylguanidine 
• 40299-87-4 N-(bromoacetyl)morpholine 
• 112257-12-2 4-(2-bromoacetyl)piperazine-1-carboxylic acid tert butyl ester 
• 75726-94-2 1-(azepan-1-yl)-2-bromoethanone 
• 1796-25-4 1-(2-bromoacetyl)piperidine 
• 90892-09-4 bromoacetopyrrolidine 
• 260788-12-3 tert-butyl 2-tosylhydrazine-1-carboxylate 
• 200813-52-1 benzyl 2-tosylhydrazine-1-carboxylate 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 98-59-9 p-toluenesulfonyl chloride 
• 536-57-2 p-toluene sulfinic acid 

Downstream Products

• 321709-95-9 4-methylbenzenesulfonic acid 1,1,3,3-tetramethylguanidine salt 

Relevant articles and documents

α-Bromodiazoacetamides - a new class of diazo compounds for catalyst-free, ambient temperature intramolecular C-H insertion reactions

In this work, we introduce a new class of halodiazocarbonyl compounds, α-halodiazoacetamides, which through a metal-free, ambient-temperature thermolysis perform intramolecular C-H insertions to produce α-halo-β-lactams. When carried out with α-bromodiazoacetamides bearing cyclic side chains, the thermolysis reaction affords bicyclic α-halo-β-lactams, in some cases in excellent yields, depending on the ring size and substitution pattern of the cyclic amide side chains.

Insights into sulfinate formation from tosyl hydrazides

Benzylation of 1,2-ditosylhydrazine in DMF under various basic conditions results in a benzyl sulfone via intermediary sulfinate formation, providing new insights and allowing practical conclusions to be drawn. The half-lives of 1,2-ditosylhydrazine and several monotosylated hydrazides with 1,1,3,3-tetramethylguanidine in DMSO have been determined by 1H NMR spectroscopy and are found to vary from a few minutes to several months. In the course of this work a benzylated, partly detosylated compound has been identified and a 1,1,3,3-tetramethyl guanidine-containing side-product characterized. A contradictory report is also commented on.