136055-16-8

Basic information

• Product Name: 2,4,6-Triisopropyl-benzenesulfonic acid 1-((2R,3R,4R,5R)-3,4-bis-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl ester
• Synonyms: 2,4,6-Triisopropyl-benzenesulfonic acid 1-((2R,3R,4R,5R)-3,4-bis-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl ester
• CAS NO: 136055-16-8
• Molecular Weight: 727.155
• Mol File: 136055-16-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,4,6-Triisopropyl-benzenesulfonic acid 1-((2R,3R,4R,5R)-3,4-bis-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-Triisopropyl-benzenesulfonic acid 1-((2R,3R,4R,5R)-3,4-bis-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl ester(136055-16-8)
• EPA Substance Registry System: 2,4,6-Triisopropyl-benzenesulfonic acid 1-((2R,3R,4R,5R)-3,4-bis-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan-2-yl)-2-oxo-1,2-dihydro-pyrimidin-4-yl ester(136055-16-8)

Safety Data

• Hazardous Substances Data: 136055-16-8(Hazardous Substances Data)

Upstream product

• 58-96-8 uridine 
• 6553-96-4 2,4,6-triisopropylphenylsulfonyl chloride 
• 10457-16-6 2',3',5,-tris-O-(trimethylsilyl)uridine 

Downstream Products

• 13957-31-8 4-thiouridine 
• 154665-03-9 5′-O-(4,4′-dimethoxytrityl)-2′-O-(tert-butyldimethylsilyl)-4-(2-cyanoethylthio)uridine 
• 170660-46-5 4-S-(2-cyanoethyl)-5'-O-(4,4'-dimethoxytrityl)-4-thiouridine 

Relevant articles and documents

Synthesis and stability of S-cyanoethyl-protected 4-thiouridine and 2'-deoxy-4-thiouridine

A convenient preparation of S-(2-cyanoethyl) protected 2'-deoxy-4-thiouridine (5a) and 4-thiouridine (5b) is presented. The S-cyanoethyl protecting group is stable to reagents commonly encountered during the phosphoramidite method of solid-phase oligonucleotide synthesis, and is readily deprotected using concentrated NH4OH at 25°C.