13606-96-7

Basic information

• Product Name: N-(2-pyridinyl)pentanamide
• Synonyms: N-(2-pyridinyl)pentanamide
• CAS NO: 13606-96-7
• Molecular Formula: C10H14N2O
• Molecular Weight: 178.23096
• Mol File: 13606-96-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(2-pyridinyl)pentanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-pyridinyl)pentanamide(13606-96-7)
• EPA Substance Registry System: N-(2-pyridinyl)pentanamide(13606-96-7)

Safety Data

• Hazardous Substances Data: 13606-96-7(Hazardous Substances Data)

Upstream product

• 504-29-0 2-aminopyridine 
• 638-29-9 n-valeryl chloride 

Downstream Products

• 1374639-81-2 2-butyl-3-benzoylimidazo[1,2-a]pyridine 

Relevant articles and documents

Lewis Base-Boryl Radicals Enabled the Desulfurizative Reduction and Annulation of Thioamides

A new protocol for radical transformations of thioamides promoted by Lewis base-boryl radicals is reported. The desulfurizative reduction to access organic amines was enabled utilizing 4-dimethylaminopyridine-BH3 as the boryl radical precursor and PhSH as the polarity reversal catalyst. Alternatively, the chain process for unsaturated thioamides was switched to an annulation reaction using N-heterocyclic carbene-BH3 as the boryl radical precursor and sterically bulky Ph3CSH as the catalyst, allowing for the construction of N-heterocyclic and carbocyclic skeletons.

An improved amide coupling procedure for the synthesis of N-(pyridin-2-yl)amides

Dehydrative amide couplings with 2-pyridylamines suffer from variable yields. A mild and high-yielding synthesis of N-(pyridin-2-yl)amides employing 2-aminopyridine-N-oxides is presented as a solution.