1360620-17-2Relevant articles and documents
Stetter reactions of unsaturated 1-acyl-1H-pyrroles
Phippen, Christopher B. W.,Goldys, Anna M.,McErlean, Christopher S. P.
, p. 6957 - 6964 (2011)
α,β-Unsaturated 1-acyl-1H-pyrroles are employed as enabling units for the construction of 1,4-dicarbonyl systems using the organocatalytic Stetter reaction. The enhanced electrophilicity of the 1-acyl-1H-pyrrole unit allows for the catalytic construction of fused and non-fused pyranones from aliphatic aldehydes, is compatible with aromatic aldehydes, and also facilitates an intermolecular variant of the reaction involving both aromatic and aliphatic aldehydes.