1361400-03-4Relevant articles and documents
Palladium-catalyzed asymmetric synthesis of 2-alkynyl oxacycles
Daniels, David S. B.,Thompson, Amber L.,Anderson, Edward A.
, p. 11506 - 11510 (2012/01/11)
Oxyacetylene: Unusual palladium-catalyzed cyclizations of cyclic and acyclic propargylic carbonates give 2-alkynyl oxacycles. The reactions proceed with very high stereoselectivity for both syn- and anti-disubstituted furans and pyrans, and with exceptional regioselectivity. In addition, two-directional cyclizations of bis-propargylic carbonate substrates yield bifurans with complete stereocontrol for all diastereomers.