136220-97-8Relevant articles and documents
ANTI-VIRAL COMPOUNDS
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Paragraph 0373; 0374, (2015/11/24)
Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
Anti-Viral Compounds
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, (2010/11/03)
Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
An efficient synthesis of chiral homophenylalanine derivatives via enantioselective hydrogenation
Li, Xingshu,Yeung, Chi-Hung,Chan, Albert S. C.,Lee, Dong-Sheng,Yang, Teng-Kuei
, p. 3863 - 3867 (2007/10/03)
Chiral homophenylalanine derivatives were synthesized via enantioselective hydrogenation of 5a and 5b catalyzed by rhodium complexes bearing chiral phosphine and phosphinite legands. Enantiomeric excesses up to 96.2% were achieved when S-spiroOP(S-1) was used as a chiral ligand under 500 psi of H2 pressure in acetone.
