1363286-28-5

Basic information

• Product Name: 2-(phenoxymethyl)-4,5,6,7-tetrahydrooxazolo[5,4-c]pyridine
• Synonyms: 2-(phenoxymethyl)-4,5,6,7-tetrahydrooxazolo[5,4-c]pyridine
• CAS NO: 1363286-28-5
• Molecular Weight: 230.266
• Mol File: 1363286-28-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(phenoxymethyl)-4,5,6,7-tetrahydrooxazolo[5,4-c]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(phenoxymethyl)-4,5,6,7-tetrahydrooxazolo[5,4-c]pyridine(1363286-28-5)
• EPA Substance Registry System: 2-(phenoxymethyl)-4,5,6,7-tetrahydrooxazolo[5,4-c]pyridine(1363286-28-5)

Safety Data

• Hazardous Substances Data: 1363286-28-5(Hazardous Substances Data)

Upstream product

• 86718-22-1 ethyl 4-amino-3-hydroxy-piperidine-1-carboxylate 
• 1363287-26-6 ethyl 3-oxo-4-[(2-phenoxyacetyl)amino]piperidine-1-carboxylate 
• 1363286-25-2 ethyl 2-(phenoxymethyl)-6,7-dihydro-4H-oxazolo[5,4-c]pyridine-5-carboxylate 
• 1363286-22-9 6,7-dihydro-2-(hydroxymethyl)-oxazolo[5,4-c]pyridine-5(4H)-carboxylic acid ethyl ester 
• 1363286-19-4 2-formyl-6,7-dihydro-oxazolo[5,4-c]pyridine-5(4H)-carboxylic acid ethyl ester 
• 1363286-16-1 2-(1,2-dihydroxy-2-phenylethyl)-6,7-dihydro-oxazolo[5,4-c]pyridine-5(4H)-carboxylic acid ethyl ester 
• 1363286-13-8 6,7-dihydro-2-[(E)-2-phenylethenyl]-oxazolo[5,4-c]pyridine-5(4H)-carboxylic acid ethyl ester 
• 29976-53-2 N-ethoxycarbonyl-4-piperidone 
• 86718-22-1 ethyl (3S,4R)-4-amino-3-hydroxypiperidine-1-carboxylate 
• 701-99-5 Phenoxyacetyl chloride 
• 95629-02-0 ethyl 3-bromo-4-oxo-1-piperidinecarboxylate 

Downstream Products

• 1363281-27-9 (4-fluorophenyl)-[2-(phenoxymethyl)-6,7-dihydro-4H-oxazolo[5,4-c]pyridin-5-yl]methanone 
• 1363282-10-3 2-(phenoxymethyl)-5-(trifluoroacetyl)-4,5,6,7-tetrahydro[1,3]oxazolo[5,4-c]pyridine 
• 1363281-33-7 5-(3,5-difluorobenzoyl)-4,5,6,7-tetrahydro-2-(phenoxymethyl)-oxazolo[5,4-c]pyridine 
• 1363281-30-4 5-(cyclopropylacetyl)-4,5,6,7-tetrahydro-2-(phenoxymethyl)-oxazolo[5,4-c]pyridine 
• 1363281-86-0 1-(2-(phenoxymethyl)-6,7-dihydrooxazolo[5,4-c]pyridin-5(4H)-yl)ethan-1-one 
• 1363282-03-4 cyclopropyl(2-(phenoxymethyl)-6,7-dihydrooxazolo[5,4-c]pyridin-5(4H)-yl)methanone 
• 1363281-48-4 (2-fluorophenyl)(2-(phenoxymethyl)-6,7-dihydrooxazolo[5,4-c]pyridin-5(4H)-yl)methanone 
• 1363281-42-8 (3-fluorophenyl)(2-(phenoxymethyl)-6,7-dihydrooxazolo[5,4-c]pyridin-5(4H)-yl)methanone 
• 1363281-39-3 (2,4-difluorophenyl)(2-(phenoxymethyl)-6,7-dihydrooxazolo[5,4-c]pyridin-5(4H)-yl)methanone 
• 1363281-71-3 (3,4-difluorophenyl)(2-(phenoxymethyl)-6,7-dihydrooxazolo[5,4-c]pyridin-5(4H)-yl)methanone 
• 1363281-68-8 (2,6-difluorophenyl)(2-(phenoxymethyl)-6,7-dihydrooxazolo[5,4-c]pyridin-5(4H)-yl)methanone 
• 1363281-64-4 (2,3-difluorophenyl)(2-(phenoxymethyl)-6,7-dihydrooxazolo[5,4-c]pyridin-5(4H)-yl)methanone 
• 1363281-83-7 (2-(phenoxymethyl)-6,7-dihydrooxazolo[5,4-c]pyridin-5(4H)-yl)(pyridin-2-yl)methanone 

Relevant articles and documents

Discovery of VU0409551/JNJ-46778212: An mGlu5 Positive Allosteric Modulator Clinical Candidate Targeting Schizophrenia

Herein, we report the structure-activity relationship of a novel series of (2(phenoxymethyl)-6,7-dihydrooxazolo[5,4-c]pyridine-5(4H)-yl(aryl)methanones as potent, selective, and orally bioavailable metabotropic glutamate receptor subtype 5 (mGlu5/su