1364041-33-7

Basic information

• Product Name: (R)-methyl 2-((R)-1-(3-fluorophenyl)-2,5-dioxopyrrolidin-3-yl)-2-isocyano-2-phenylacetate
• Synonyms: (R)-methyl 2-((R)-1-(3-fluorophenyl)-2,5-dioxopyrrolidin-3-yl)-2-isocyano-2-phenylacetate
• CAS NO: 1364041-33-7
• Molecular Weight: 366.349
• Mol File: 1364041-33-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-methyl 2-((R)-1-(3-fluorophenyl)-2,5-dioxopyrrolidin-3-yl)-2-isocyano-2-phenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-methyl 2-((R)-1-(3-fluorophenyl)-2,5-dioxopyrrolidin-3-yl)-2-isocyano-2-phenylacetate(1364041-33-7)
• EPA Substance Registry System: (R)-methyl 2-((R)-1-(3-fluorophenyl)-2,5-dioxopyrrolidin-3-yl)-2-isocyano-2-phenylacetate(1364041-33-7)

Safety Data

• Hazardous Substances Data: 1364041-33-7(Hazardous Substances Data)

Upstream product

• 7508-99-8 1-(3-fluorophenyl)-1H-pyrrole-2,5-dione 
• 39533-32-9 methyl 2-isocyano-2-phenylacetate 

Relevant articles and documents

Asymmetric michael addition of α-substituted isocyanoacetates with maleimides catalyzed by chiral tertiary amine thiourea

A highly diastereoselective and enantioselective Michael addition of α-substituted isocyanoacetates with maleimides catalyzed by bifunctional tertiary amine thioureas has been developed. Various chiral succinimide derivatives bearing adjacent quaternary and tertiary stereocenters were prepared in excellent yields (up to 98%), diastereoselectivities (up to 99:1), and enantioselectivities (up to 98% ee). The synthetic utility of chiral succinimide derivatives is also demonstrated in the preparation of h5-HT1d receptor agonist motifs.