136433-45-9

Basic information

• Product Name: 3-(prop-2-en-1-yl)-4-(prop-2-en-1-yloxy)benzaldehyde
• CAS NO: 136433-45-9
• Molecular Formula: C₁₃H₁₄O₂
• Molecular Weight: 202.2491
• Mol File: 136433-45-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 319.7°C at 760 mmHg
• Flash Point: 137.9°C
• Density: 1.023g/cm³
• Vapor Pressure: 0.000334mmHg at 25°C
• Refractive Index: 1.546
• CAS DataBase Reference: 3-(prop-2-en-1-yl)-4-(prop-2-en-1-yloxy)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(prop-2-en-1-yl)-4-(prop-2-en-1-yloxy)benzaldehyde(136433-45-9)
• EPA Substance Registry System: 3-(prop-2-en-1-yl)-4-(prop-2-en-1-yloxy)benzaldehyde(136433-45-9)

Safety Data

• Hazardous Substances Data: 136433-45-9(Hazardous Substances Data)

Upstream product

• 106-95-6 allyl bromide 
• 41052-88-4 4-hydroxy-3-(2-propen-1-yl)benzaldehyde 
• 40663-68-1 4-(2-propenyloxy)benzaldehyde 
• 123-08-0 4-hydroxy-benzaldehyde 

Downstream Products

• 136433-44-8 3,5-di-(2-propenyl)-4-hydroxybenzaldehyde 
• 863659-50-1 3-(prop-1-enyl)-4-(prop-1-enyloxy)benzaldehyde 
• 10035-16-2 benzofuran-5-carbaldehyde 

Relevant articles and documents

Allylphenols as a new class of human 15-lipoxygenase-1 inhibitors

In this study, a series of mono- and diallylphenol derivative were designed, synthesized, and evaluated as potential human 15-lipoxygenase-1 (15-hLOX-1) inhibitors. Radical scavenging potency of the synthetic allylphenol derivatives was assessed and the results were in accordance with lipoxygenase (LOX) inhibition potency. It was found that the electronic natures of allyl moiety and para substituents play the main role in radical scavenging activity and subsequently LOX inhibition potency of the synthetic inhibitors. Among the synthetic compounds, 2,6-diallyl-4-(hexyloxy)phenol (42) and 2,6-diallyl-4-aminophenol (47) showed the best results for LOX inhibition (IC50 = 0.88 and 0.80 μM, respectively).

An isomerization-ring-closing metathesis strategy for the synthesis of substituted benzofurans

Twelve substituted benzofurans were synthesized from their corresponding substituted 1-allyl-2-allyloxybenzenes using ruthenium-mediated C- and O-allyl isomerization followed by ring-closing metathesis.