1364440-77-6

Basic information

• Product Name: C₁₉H₁₅N₃O
• CAS NO: 1364440-77-6
• Molecular Weight: 301.348
• Mol File: 1364440-77-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₁₅N₃O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₁₅N₃O(1364440-77-6)
• EPA Substance Registry System: C₁₉H₁₅N₃O(1364440-77-6)

Safety Data

• Hazardous Substances Data: 1364440-77-6(Hazardous Substances Data)

Upstream product

• 3939-09-1 2,4-difluorobenzonitrile 
• 1364440-74-3 C₁₂H₇FN₂O 
• 100-46-9 benzylamine 

Relevant articles and documents

New aromatase inhibitors from the 3-pyridyl arylether and 1-aryl pyrrolo[2,3-c]pyridine series

Aromatase inhibition is the new standard of care for estrogen receptor positive breast cancer and has also potential for treatment of other diseases such as endometriosis. Simple and readily available 3-pyridyl arylethers and 1-aryl pyrrolo[2,3-c]pyridines recapitulating the key pharmacophore elements of Letrozole (1) are described and their structure-activity relationships are discussed. Potent and ligand efficient leads such as compound 23 (IC 50 = 59 nM on aromatase) have been identified.