1364632-45-0

Basic information

• Product Name: (S)-(tetrahydrofuran-3-yl)hydrazine hydrochloride
• Synonyms: (S)-(tetrahydrofuran-3-yl)hydrazine hydrochloride;(3S)-tetrahydrofuran-3-ylhydrazine hydrochloride;[(3S)-Tetrahydro-3-furanyl]hydrazine hydrochloride;(3S)oxolane-3-ylhydrazine hydrochloride
• CAS NO: 1364632-45-0
• Molecular Formula: C4H11ClN2O
• Molecular Weight: 138.59594
• Mol File: 1364632-45-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-(tetrahydrofuran-3-yl)hydrazine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(tetrahydrofuran-3-yl)hydrazine hydrochloride(1364632-45-0)
• EPA Substance Registry System: (S)-(tetrahydrofuran-3-yl)hydrazine hydrochloride(1364632-45-0)

Safety Data

• Hazardous Substances Data: 1364632-45-0(Hazardous Substances Data)

Usage

General Description

(S)-(tetrahydrofuran-3-yl)hydrazine hydrochloride is a chemical compound that is used in pharmaceutical research and development. It is the hydrochloride salt of the compound (S)-(tetrahydrofuran-3-yl)hydrazine, which is a derivative of tetrahydrofuran, a cyclic ether. Hydrazine is a functional group that contains two nitrogen atoms and is commonly found in various organic compounds. The hydrochloride salt form of this compound is often used to improve the solubility and stability of the compound in aqueous solutions. This chemical has potential applications in the synthesis of various pharmaceuticals and may have biological activity that could be useful in the development of new drugs.

Upstream product

• 1429510-48-4 (S)-t-butyl 1-(tetrahydrofuran-3-yl)hydrazinecarboxylate 
• 1429510-92-8 (-)-benzyl 2-(tetrahydrofuran-3-yl)hydrazinecarboxylate 
• 86087-24-3 (R)-3-Hydroxytetrahydrofuran 

Downstream Products

• 1429510-43-9 ethyl 5-(4-bromo-2,5-difluorophenyl)-1-[(S)-tetrahydrofuran-3-yl]-1H-pyrazole-4-carboxylate 
• 1429510-33-7 ethyl 5-(4-bromo-2-fluorophenyl)-1-[(S)-tetrahydrofuran-3-yl]-1H-pyrazole-4-carboxylate 
• 1429510-35-9 ethyl 5-(4-bromo-2-nitrophenyl)-1-[(S)-tetrahydrofuran-3-yl]-1H-pyrazole-4-carboxylate 

Relevant articles and documents

COMPOUNDS USEFUL AS KINASE INHIBITORS

This invention relates to novel compounds. The compounds of the invention are tyrosine kinase inhibitors. Specifically, the compounds of the invention are useful as inhibitors of Bruton's tyrosine kinase (BTK).The invention also contemplates the use of the compounds for treating conditions treatable by the inhibition of Bruton's tyrosine kinase, for example cancer, lymphoma, leukemia and immunological diseases.

SALT OF PYRAZOLOQUINOLINE DERIVATIVE, AND CRYSTAL THEREOF

The present invention provides a salt of (S)-7-(2-methoxy-3,5-dimethylpyridin-4-yl)-1-(tetrahydrofuran-3-yl)-1H-pyrazolo[4,3-c]quinolin-4(5H)-one and an acid selected from the group consisting of hydrochloric acid, hydrobromic acid, sulfuric acid, nitric