1364691-93-9

Basic information

• Product Name: 4-((1H-1,2,4-triazol-1-yl)methyl)-2-(4-(tetrahydro-2H-pyran-2-yloxy)but-1-ynyl)benzenamine
• Synonyms: 4-((1H-1,2,4-triazol-1-yl)methyl)-2-(4-(tetrahydro-2H-pyran-2-yloxy)but-1-ynyl)benzenamine
• CAS NO: 1364691-93-9
• Molecular Weight: 0
• Mol File: 1364691-93-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-((1H-1,2,4-triazol-1-yl)methyl)-2-(4-(tetrahydro-2H-pyran-2-yloxy)but-1-ynyl)benzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((1H-1,2,4-triazol-1-yl)methyl)-2-(4-(tetrahydro-2H-pyran-2-yloxy)but-1-ynyl)benzenamine(1364691-93-9)
• EPA Substance Registry System: 4-((1H-1,2,4-triazol-1-yl)methyl)-2-(4-(tetrahydro-2H-pyran-2-yloxy)but-1-ynyl)benzenamine(1364691-93-9)

Safety Data

• Hazardous Substances Data: 1364691-93-9(Hazardous Substances Data)

Upstream product

• 119192-10-8 4-(1H-1,2,4-triazol-1-ylmethyl)aniline 
• 40365-61-5 2-(but-3-yn-1-yloxy)tetrahydropyran 
• 160194-26-3 4-((1H-1,2,4-triazol-1-yl)methyl)-2-iodobenzenamine 
• 110-87-2 3,4-dihydro-2H-pyran 

Downstream Products

• 208941-96-2 2-(5-((1H-1,2,4-triazol-1-yl)methyl)-1H-indol-2-yl)-N,N-dimethylethanamine 
• 1364692-00-1 tert-butyl 4-((1H-1,2,4-triazol-1-yl)-methyl)-2-(4-(tetrahydro-2H-pyran-2-yloxy)but-1-ynyl)-phenylcarbamate 

Relevant articles and documents

Efficient synthesis of impurity-C of antimigraine agent Rizatriptan benzoate

During the commercial manufacturing of antimigraine drug Rizatriptan benzoate, several impurities are reported to be formed. This present work demonstrates a convergent and short synthesis of the most critical impurity (C) of Rizatriptan, [2-(5-((1H-1,2,4-triazol-1-yl)methyl)-1H-indole-2-yl)-N,N- dimethylethanamine (1)], recently reported in U.S. Pharmacopeia.