136538-85-7 Usage
Description
6-IODOACETAMIDOTETRAMETHYLRHODAMINE, also known as IATR, is a thiol-reactive fluorescent probe derived from the rhodamine family of dyes. It is characterized by its purple solid appearance and is known for its brightness and resistance to photobleaching, making it a valuable tool in fluorescence microscopy.
Uses
Used in Fluorescence Microscopy:
6-IODOACETAMIDOTETRAMETHYLRHODAMINE is used as a fluorescent probe for labeling proteins. Its application in fluorescence microscopy is due to its brightness and resistance to photobleaching, which allows for clear and stable visualization of proteins within cells.
Used in Protein Conformation Studies:
6-IODOACETAMIDOTETRAMETHYLRHODAMINE is used as a tool for studying changes in the orientation and mobility of proteins. Its application in fluorescence anisotropy measurements helps researchers understand the dynamic behavior of proteins and their interactions within biological systems.
Used in Research and Diagnostics:
6-IODOACETAMIDOTETRAMETHYLRHODAMINE is used as a reagent in various research and diagnostic applications, particularly in the field of biochemistry and molecular biology. Its thiol reactivity enables the specific labeling of proteins, facilitating the study of their structure, function, and interactions with other biomolecules.
Used in Pharmaceutical Development:
6-IODOACETAMIDOTETRAMETHYLRHODAMINE may also be utilized in the development of new drugs and therapies, particularly those targeting protein-based diseases. Its ability to label proteins allows for the identification and characterization of potential drug targets, as well as the evaluation of drug candidates' interactions with these targets.
Used in Analytical Chemistry:
6-IODOACETAMIDOTETRAMETHYLRHODAMINE is used as an analytical tool in various chemical assays and techniques, such as high-performance liquid chromatography (HPLC) and capillary electrophoresis (CE). Its fluorescent properties enable the sensitive detection and quantification of proteins and other biomolecules in complex samples.
Used in Biotechnology:
6-IODOACETAMIDOTETRAMETHYLRHODAMINE is used in biotechnology applications, such as the development of biosensors and the study of protein-protein interactions. Its ability to label proteins with high specificity makes it a valuable tool for the design and optimization of biotechnological systems and processes.
Check Digit Verification of cas no
The CAS Registry Mumber 136538-85-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,5,3 and 8 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 136538-85:
(8*1)+(7*3)+(6*6)+(5*5)+(4*3)+(3*8)+(2*8)+(1*5)=147
147 % 10 = 7
So 136538-85-7 is a valid CAS Registry Number.
InChI:InChI=1/C26H24IN3O4/c1-29(2)16-6-9-20-22(12-16)33-23-13-17(30(3)4)7-10-21(23)26(20)19-8-5-15(28-24(31)14-27)11-18(19)25(32)34-26/h5-13H,14H2,1-4H3,(H,28,31)
