136548-01-1

Basic information

• Product Name: L-Glutamic acid, N-[4-[4-(2,6-diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-1-methylenebutyl] benzoyl]-, dimethyl ester
• CAS NO: 136548-01-1
• Molecular Formula: C23H29N5O6
• Molecular Weight: 471.513
• Mol File: 136548-01-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Glutamic acid, N-[4-[4-(2,6-diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-1-methylenebutyl] benzoyl]-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Glutamic acid, N-[4-[4-(2,6-diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-1-methylenebutyl] benzoyl]-, dimethyl ester(136548-01-1)
• EPA Substance Registry System: L-Glutamic acid, N-[4-[4-(2,6-diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-1-methylenebutyl] benzoyl]-, dimethyl ester(136548-01-1)

Safety Data

• Hazardous Substances Data: 136548-01-1(Hazardous Substances Data)

Upstream product

• 136527-57-6 methyl 4-<5-(2,4-diamino-6(1H)-pyrimidinon-5-yl)-pent-1-en-2-yl>benzoate 
• 136527-56-5 methyl 4-(6-carboethoxy-6-cyanohex-1-en-2-yl)benzoate 
• 136527-55-4 methyl 4-(5-methylsulfonyloxypent-1-en-2-yl)benzoate 
• 136527-53-2 methyl 4-(5-acetoxypent-1-en-2-yl)benzoate 
• 136527-54-3 methyl 4-(5-hydroxypent-1-en-2-yl)benzoate 
• 23150-65-4 L-glutamic dimethyl ester hydrochloride 
• 136527-58-7 4-<5-(2,4-diamino-6(1H)-pyrimidinon-5-yl)-pent-1-en-2-yl>benzoic acid 

Downstream Products

• 136527-62-3 N-<4-<5-(2,4-diamino-6(1H)-pyrimidinon-5-yl)-pent-1-hydroxy-2-yl>benzoyl>-L-glutamic acid 
• 139577-65-4 N-<4-<5-(2,4-diamino-6(1H)-pyrimidinon-5-yl)-pent-2-yl>benzoyl>-L-glutamic acid 
• 136527-61-2 dimethyl N-<4-<5-(2,4-diamino-6(1H)-pyrimidinone-5-yl)-pent-1-hydroxy-2-yl>benzoyl>-L-glutamate 
• 139577-61-0 dimethyl N-<4-<5-(2,4-diamino-6(1H)-pyrimidinon-5-yl)-pent-2-yl>benzoyl>-L-glutamate 
• 136527-59-8 N-<4-<5-(2,4-diamino-6(1H)-pyrimidinon-5-yl)-pent-1-en-2-yl>benzoyl>-L-glutamic acid 

Relevant articles and documents

Synthesis of 10-substituted "open-chain" analogues of 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF, lometrexol)

Several novel and very potent folate antimetabolites, structurally based upon our previously described "open-chain" version of DDATHF but carrying 1-carbon substituents in the 10-position, have been synthesized. A key synthetic sequence involving a pallad