136679-70-4

Basic information

• Product Name: 5-diphenylphosphinoylmethyl-3-propyl-4,5-dihydroisoxazole
• Synonyms: 5-diphenylphosphinoylmethyl-3-propyl-4,5-dihydroisoxazole
• CAS NO: 136679-70-4
• Molecular Weight: 327.363
• Mol File: 136679-70-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-diphenylphosphinoylmethyl-3-propyl-4,5-dihydroisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-diphenylphosphinoylmethyl-3-propyl-4,5-dihydroisoxazole(136679-70-4)
• EPA Substance Registry System: 5-diphenylphosphinoylmethyl-3-propyl-4,5-dihydroisoxazole(136679-70-4)

Safety Data

• Hazardous Substances Data: 136679-70-4(Hazardous Substances Data)

Upstream product

• 1079-66-9 chloro-diphenylphosphine 
• 14655-53-9 allyloxy-diphenylphosphane 
• 4141-48-4 allyldiphenylphosphine oxide 
• 71494-96-7 Butyronitrile oxide 
• 110-69-0 butyraldehyde oxime 

Downstream Products

• 5622-72-0 1-Propyl-but-3-enylamine 
• 136679-82-8 4-amino-1-diphenylphosphinoylheptan-2-ol 

Relevant articles and documents

A New Method for Stereoselective Homoallylic Amine Synthesis

Nitrile oxide cycloadditions to readily available allylic diphenylphosphine oxides 2 proceeded regioselectively and stereoselectively to give 5-(1'-diphenylphosphinoylalkyl)isoxazolines 4 and 5.These heterocycles were reduced to δ-amino-β-hydroxyalkyldiphenylphosphine oxides 6 and 7 using a combination of sodium borohydride and nickel(II) chloride.Stereospecific elimination of diphenylphosphinic acid from the reduction products using sodium hydride in N,N-dimethylformamide gave homoallylic primary amines 8 and 9 of defined stereochemistry.