136693-06-6

Basic information

• Product Name: N-((1S,2R)-2-hydroxy-1-phenyl-3-butenyl)benzamide
• CAS NO: 136693-06-6
• Molecular Weight: 267.327
• Mol File: 136693-06-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-((1S,2R)-2-hydroxy-1-phenyl-3-butenyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-((1S,2R)-2-hydroxy-1-phenyl-3-butenyl)benzamide(136693-06-6)
• EPA Substance Registry System: N-((1S,2R)-2-hydroxy-1-phenyl-3-butenyl)benzamide(136693-06-6)

Safety Data

• Hazardous Substances Data: 136693-06-6(Hazardous Substances Data)

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 163010-72-8 N-benzoyl-(S)-phenylglycinal 

Relevant articles and documents

Stereoselective intramolecular cyclization of allyl and homoallyl benzamide via π-allylpalladium complex catalyzed by Pd(0)

The transformation of acyclic allylic benzamides 4 and homoallylic benzamides 12 to vinyl oxazolines 3 is achieved in the presence of base by the catalysis and Pd(0) in high yield and with high diastereoselectivity. Especially, in the case of homoallylic benzamides 12, trans-oxazolines 3 are formed exclusively or predominantly over cis-oxazolines 8, irrespective of the composition of their stereoisomers. The reaction is believed to proceed via the same π-allylpalladium complex that arises from either primary or secondary allylic acetates. We applied this method to the syntheses of β- amino-α-hydroxy acids 1 and γ-amino-β-hydroxy acids 2, conveniently protected as oxazoline.