136725-51-4 Usage
General Description
The chemical "(R)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid benzyl ester" is a compound that is primarily used as a reagent in organic synthesis. It consists of a pyrrolidine ring with a toluene-4-sulfonyloxy group attached to the third position, and a benzyl ester group attached to the carboxylic acid. (R)-3-(Toluene-4-sulfonyloxy)-pyrrolidine-1-carboxylic acid benzyl ester is commonly utilized in the preparation of a variety of organic molecules, including pharmaceuticals and natural products. Its unique structure and reactivity make it a valuable building block in the chemical industry, particularly for the creation of complex molecular structures. Additionally, the compound has potential applications in medicinal and biochemical research due to its ability to modify and manipulate organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 136725-51-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,7,2 and 5 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 136725-51:
(8*1)+(7*3)+(6*6)+(5*7)+(4*2)+(3*5)+(2*5)+(1*1)=134
134 % 10 = 4
So 136725-51-4 is a valid CAS Registry Number.
136725-51-4Relevant articles and documents
Stability against enzymatic hydrolysis of endomorphin-1 analogues containing β-proline
Cardillo, Giuliana,Gentilucci, Luca,Tolomelli, Alessandra,Calienni, Maria,Qasem, Ahmed R.,Spampinato, Santi
, p. 1498 - 1502 (2007/10/03)
The enantiomer of endomorphin-1 (Tyr-Pro-Trp-PheNH2) and the analogues containing (S)-or (R)-β-proline have been synthesized, and their affinities towards μ-opioid receptors have been measured. As expected, the incubations of the different peptides with some commercially available enzymes showed that the presence of D-residues gave strong resistance towards digestion. The presence of β-proline alone is sufficient to confer good resistance against the hydrolysis of the biologically strategic Pro-Trp bond.
Constrained β-alanine based GpIIb/IIIa antagonists
Klein, Scott I.,Czekaj, Mark,Molino, Bruce F.,Valeria, Chu
, p. 1773 - 1778 (2007/10/03)
The concepts of centrally constrained and peptide based fibrinogen receptor antagonists have been successfully combined into a single series of analogs which have been demonstrated to be potent inhibitors of platelet aggregation.
