136765-48-5

Basic information

• Product Name: NORTRIPTYLINE-D3 HYDROCHLORIDE
• Synonyms: NORTRIPTYLINE-D3 HYDROCHLORIDE;NORTRIPTYLINE HCL (D3);NORTRIPTYLINE HCL (METHYL-D3);1-Propanamine, 3-(10,11-dihydro-5H-dibenzoa,dcyclohepten-5-ylidene)-N-(methyl-d3)-;NORTRIPTYLINE-D3HYDROCHLORIDE,100/ML(FREEBASE)INMETHANOL;Nortriptyline-D3 hydrochloride solution;Nortriptyline-d3;NORTRIPTYLINE-D3 HCL (N-METHYL-D3)
• CAS NO: 136765-48-5
• Molecular Formula: C19H19ClD3N
• Molecular Weight: 302.86
• EINECS: 200-659-6
• Mol File: 136765-48-5.mol
• Article Data: 0

Chemical Properties

• Flash Point: 9℃
• Appearance: /
• Storage Temp.: ?20°C
• CAS DataBase Reference: NORTRIPTYLINE-D3 HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: NORTRIPTYLINE-D3 HYDROCHLORIDE(136765-48-5)
• EPA Substance Registry System: NORTRIPTYLINE-D3 HYDROCHLORIDE(136765-48-5)

Safety Data

• Hazard Codes: F,T
• Statements: 11-23/24/25-39/23/24/25
• Safety Statements: 7-16-36/37-45
• RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
• WGK Germany: 2
• Hazardous Substances Data: 136765-48-5(Hazardous Substances Data)

Usage

Description

Nortriptyline-D3 Hydrochloride, a second-generation tricyclic antidepressant (TCA), is an active metabolite of the TCA amitriptyline. It is marketed under various trade names, such as Sensoval, Aventyl, and Pamelor, and is primarily used for the treatment of major depression. This certified Snap-N-Spike Solution serves as an internal standard for the quantitation of nortriptyline levels in various applications, including clinical toxicology, forensic analysis, urine drug testing, isotope dilution methods, and medication monitoring.

Uses

Used in Clinical Toxicology:
Nortriptyline-D3 Hydrochloride is used as an internal standard for the accurate quantitation of nortriptyline levels in clinical toxicology. This helps in determining the presence and concentration of the drug in biological samples, which is crucial for understanding the potential toxic effects and managing overdose situations.
Used in Forensic Analysis:
In forensic analysis, Nortriptyline-D3 Hydrochloride is utilized as an internal standard to ensure the precise measurement of nortriptyline levels in biological samples. This aids in investigations involving drug-related fatalities or cases where the presence of the drug may be of legal significance.
Used in Urine Drug Testing:
Nortriptyline-D3 Hydrochloride is employed as an internal standard in urine drug testing to accurately determine the presence and concentration of nortriptyline in urine samples. This is essential for monitoring patients undergoing antidepressant therapy and ensuring adherence to prescribed medication regimens.
Used in Isotope Dilution Methods:
Nortriptyline-D3 Hydrochloride is used as an internal standard in isotope dilution methods to enhance the accuracy and precision of nortriptyline level measurements. This technique is particularly useful in research and development, as well as in the quality control of pharmaceutical products.
Used in Medication Monitoring Applications:
In medication monitoring applications, Nortriptyline-D3 Hydrochloride serves as an internal standard to ensure the precise quantitation of nortriptyline levels in patients undergoing antidepressant therapy. This helps healthcare professionals to assess the effectiveness of the treatment, make necessary adjustments to the dosage, and minimize the risk of adverse effects.
Overall, Nortriptyline-D3 Hydrochloride plays a vital role in various applications across different industries, including clinical toxicology, forensic analysis, urine drug testing, isotope dilution methods, and medication monitoring. Its use as an internal standard ensures accurate and reliable quantitation of nortriptyline levels, which is essential for patient care, research, and legal investigations.