136827-57-1

Basic information

• Product Name: 4-[(E)-2-(4-hydroxyphenyl)ethenyl]benzonitrile
• Synonyms: 4-[(E)-2-(4-hydroxyphenyl)ethenyl]benzonitrile
• CAS NO: 136827-57-1
• Molecular Weight: 221.258
• Mol File: 136827-57-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 4-[(E)-2-(4-hydroxyphenyl)ethenyl]benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(E)-2-(4-hydroxyphenyl)ethenyl]benzonitrile(136827-57-1)
• EPA Substance Registry System: 4-[(E)-2-(4-hydroxyphenyl)ethenyl]benzonitrile(136827-57-1)

Safety Data

• Hazardous Substances Data: 136827-57-1(Hazardous Substances Data)

Upstream product

• 5462-71-5 4-cyanophenylacetic acid 
• 123-08-0 4-hydroxy-benzaldehyde 
• 74189-56-3 4-(tetrahydropyran-2-yloxy)benzaldehyde 
• 112681-06-8 As-(p-cyanobenzyl)triphenylarsonium bromide 
• 57193-97-2 (E)-4-cyano-4'-methoxystilbene 
• 3435-51-6 4-ethenylbenzonitrile 
• 619-65-8 4-cyanobenzoic Acid 
• 28255-72-3 4-Cyanphenylphosphonsaeurediethylester 
• 123-11-5 4-methoxy-benzaldehyde 
• 17201-43-3 4-cyanobenzyl bromide 

Downstream Products

• 724464-66-8 4-{2-[4-(9-hydroxy-nonyloxy)-phenyl]-vinyl}-benzonitrile 
• 724464-67-9 4-{2-[4-(11-hydroxy-undecyloxy)-phenyl]-vinyl}-benzonitrile 
• 73351-21-0 4-(((4-methoxyphenyl)amino)methyl)phenol 
• 114046-25-2 4-(((4-methoxyphenyl)imino)methyl)benzonitrile 
• 3230-50-0 4-(4-hydroxyphenyl)-N-(4-methoxyphenyl)imine 
• 1009342-47-5 4-[2-(4-tetradeca-11,13-dienyloxy-phenyl)-vinyl]-benzonitrile 
• 1009342-41-9 4-{2-[4-(11-oxo-undecyloxy)-phenyl]-vinyl}-benzonitrile 
• 1009342-40-8 4-{2E-[4-(9-oxononyloxy)phenyl]vinyl}benzonitrile 
• 1009342-39-5 4-{2-[4-(7-oxo-heptyloxy)-phenyl]-vinyl}-benzonitrile 
• 1009342-37-3 4-{2-[4-(6-oxo-hexyloxy)-phenyl]-vinyl}-benzonitrile 
• 1009342-36-2 4-{2-[4-(6-hydroxy-hexyloxy)-phenyl]-vinyl}-benzonitrile 
• 724464-65-7 4-{2-[4-(7-hydroxy-heptyloxy)-phenyl]-vinyl}-benzonitrile 

Relevant articles and documents

Ultrafast proton transfer dynamics of hydroxystilbene photoacids

The effects of 4-cyano and 3-cyano substituents on the spectroscopic properties and photoacidity of 3- and 4-hydroxystilbene have been investigated. In nonpolar solvents, the 3-hydroxycyanostilbenes have much longer singlet lifetimes and larger fluorescen

Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation

Inhibition of lysine-specific demethylase 1 (LSD1) has recently emerged as an attractive therapeutic target for treating cancer and other diseases. As a continuity of our ongoing effort to identify novel small-molecule LSD1-inhibitors, we designed and syn

Synthesis and cytotoxic effects on pancreatic cancer cells of resveratrol analogs

In this study, a series of resveratrol analogs was synthesized and the effects on the viability of pancreatic cancer cell lines were evaluated. The new molecules were designed by removing the 3- and 5-OH groups of resveratrol, and by incorporating other s

Resveratrol derivative, preparation method thereof and application of resveratrol derivative serving as LSD1 inhibitor

The invention discloses a resveratrol derivative, a synthesizing method thereof and application of the resveratrol derivative serving as a histone lysine specificity demethylase 1 inhibitor and belongs to the field of medicinal chemistry. The formula of the resveratrol derivative is as shown in the specification, wherein R is preferably hydrogen, hydroxyl, methoxy, nitro or halogen, and X represents N atom and C atom. The resveratrol derivative has good inhibitory effect on the histone lysine specificity demethylase 1 and can be used as the candidate for further development or the lead compound to develop medicine for treating diseases such as tumors and AIDS.