136869-41-5Relevant articles and documents
Fluoride as leaving group in SRN1 reactions of a tetrasubstituted-1,4-benzoquinone
Crozet, Michel P.,Giraud, Luc,Sabuco, Jean-Francois,Vanelle, Patrice
, p. 1063 - 1064 (1992)
2-Fluoromethyl-3,5,6-trimethyl-1,4-benzoquinone was synthesized and its reactivity in SRN1 reactions compared to the reactivity of the chloro derivative previously described. This study reports the first examples of the displacement of the fluoride in SRN1 reactions involving a substitution at an sp3 carbon atom.
S(RN)1 reactions of a tetrasubstituted-1,4-benzoquinone
Crozet,Giraud,Sabuco,Vanelle,Barreau
, p. 4125 - 4128 (2007/10/02)
The C-alkylation reaction of 2-chloromethyl-3,5,6-trimethyl-1,4-benzoquinone by 2-nitropropane anion is shown to proceed by the S(RN)1 mechanism. This mechanism is confirmed by the inhibitory effects of dioxygen, p-dinitrobenzene, cupric chloride and di-t